Investigation of Cytotoxic Effects of Inula Viscosa Extract

Ceylan Hepokur; Yakup Budak; Hasan Basri Karayel; Bedrettin Selvi; İlhan Yaylım

doi:10.17776/csj.437993

EN

Investigation of Cytotoxic Effects of Inula Viscosa Extract

Abstract

Inula viscosa is a type of Asteraceae family, which widely used for medicinal plant to treatment of different diseases. Inula viscosa contains many biological compounds, such as monoterpenes, sesquiterpenes, diterpenes, flavonoids. Our study aimed to investigate the cytotoxic effects of Inula viscosa extract on MCF-7 (breast carcinoma), C6 (glioblostoma cancer), MG63 (bone osteosarcoma), cancer cells and L929 (mouse fibroblostama) cell lines. Cytotoxic effects of the Inula viscosa extracts were performed by XTT assay. In this study, Inula viscosa extracts showed selective cytotoxic effect on MC-7 compared than L929 cells. The Inula viscosa extracts appear to be a promising source of new anticancer agent. Further studies are needed to identify the cytotoxic activity mechanisms on these cancer cell lines.

Keywords

Cancer,Cytotoxic Effect

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Ceylan Hepokur ^*
Türkiye

Yakup Budak

Hasan Basri Karayel

Bedrettin Selvi

İlhan Yaylım

Publication Date

September 30, 2019

Submission Date

June 28, 2018

Acceptance Date

July 2, 2019

Published in Issue

Year 2019 Volume: 40 Number: 3

DOI

https://doi.org/10.17776/csj.437993

IZ

https://izlik.org/JA43GZ83JX

Cite

RIS / Bibtex

APA

Hepokur, C., Budak, Y., Karayel, H. B., Selvi, B., & Yaylım, İ. (2019). Investigation of Cytotoxic Effects of Inula Viscosa Extract. Cumhuriyet Science Journal, 40(3), 578-582. https://doi.org/10.17776/csj.437993

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Investigation of Cytotoxic Effects of Inula Viscosa Extract

Öz

Investigation of Cytotoxic Effects of Inula Viscosa Extract

Abstract

Keywords

References

Details

Primary Language

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Publication Date

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Acceptance Date

Published in Issue

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Cited By

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Anticancer, Antioxidant, Antimicrobial and Enzyme Inhibitory Activities of Inula aucheriana

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Antineoplastic Properties by Proapoptotic Mechanisms Induction of Inula viscosa and Its Sesquiterpene Lactones Tomentosin and Inuviscolide

Inula viscosa (L.) Aiton Ethanolic Extract Inhibits the Growth of Human AGS and A549 Cancer Cell Lines

Apoptotic and antiproliferative effects of Inula viscosa L. water extract in the expression of microRnas on HCT 116 cell line: an in vitro study

Molecular characterization of Dittrichia viscosa (L.) greuter (Asteraceae) populations revealed by ISSR markers and chloroplast (CPDNA) tRNL intron sequences

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One–pot green synthesis of TiO2 nanoparticles using Inula Viscosa leaf extract as an efficient photocatalyst for organic dyes removal

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