@article{article_437993, title={Investigation of Cytotoxic Effects of Inula Viscosa Extract}, journal={Cumhuriyet Science Journal}, volume={40}, pages={578–582}, year={2019}, DOI={10.17776/csj.437993}, author={Hepokur, Ceylan and Budak, Yakup and Karayel, Hasan Basri and Selvi, Bedrettin and Yaylım, İlhan}, keywords={Cancer,Cytotoxic Effect}, abstract={
Inula viscosa is a type of Asteraceae
family, which widely used for
medicinal plant to treatment of different diseases. Inula viscosa contains many biological compounds, such as monoterpenes,
sesquiterpenes, diterpenes, flavonoids. Our study
aimed to investigate the cytotoxic effects of Inula viscosa extract on MCF-7 (breast carcinoma), C6 (glioblostoma
cancer), MG63 (bone osteosarcoma), cancer cells and L929 (mouse fibroblostama)
cell lines. Cytotoxic effects of the Inula
viscosa extracts were performed by XTT assay. In this study, Inula viscosa extracts showed selective
cytotoxic effect on MC-7 compared than L929 cells. The Inula
viscosa extracts appear
to be a promising source of new anticancer agent . Further studies are needed to identify the
cytotoxic activity mechanisms on these cancer cell lines.
}, number={3}, publisher={Sivas Cumhuriyet Üniversitesi} }