The Hypoglycaemic Effect and Antioxidant and Anti-α-amylase Activity of the Hydroalcoholic Extract of Tamarix algeriensis G.Nicholson Tamaricaceae

Mohammed Tahar Ben Moussa; Chihab Eddine Zeggada; Abdallah Mouadh Rahmani; Hassina Harkat; Safa Chaira; Nawal Achachi

doi:10.17776/csj.1818332

The Hypoglycaemic Effect and Antioxidant and Anti-α-amylase Activity of the Hydroalcoholic Extract of Tamarix algeriensis G.Nicholson Tamaricaceae

Abstract

This study evaluated the hydroalcoholic extract of Tamarix algeriensis aerial parts' antihyperglycemic and antioxidant properties. In Batna, Algeria, the researchers gathered the plant's aerial parts, which they then macerated to create the extract. Numerous bioactive substances, such as flavonoids, saponins, polyphenols, steroids, terpenoids, tannins, and anthracene glycosides, were found during the initial phytochemical screening. Numerous techniques, such as ferric reducing power (FRAP), total antioxidant capacity (TAC), and DPPH free radical scavenging tests, were used to confirm the extract's strong antioxidant activity in vitro. Additionally, the extract demonstrated strong inhibitory activity against the enzyme α-amylase, which is essential for the breakdown of carbohydrates. Tamarix algeriensis extract significantly decreased blood glucose levels after a glucose load in in vivo tests on normoglycaemic mice, demonstrating a hypoglycaemic effect. These findings imply that Tamarix algeriensis hydroalcoholic extract may be a useful source of therapeutic compounds for the treatment of diabetes and oxidative stress.

Keywords

Supporting Institution

faculty of medecine Annaba

Ethical Statement

IRB

Thanks

The writers acknowledge the Algerian Ministry of Higher Education and Scientific Research for their assistance inside the context of the PRFU project (approval n° B00L01UN052).

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Details

Primary Language

English

Subjects

Plant Biochemistry

Journal Section

Research Article

Authors

Mohammed Tahar Ben Moussa ^*
0000-0002-0316-2887
Algeria

Chihab Eddine Zeggada
0009-0002-0414-5904
Algeria

Abdallah Mouadh Rahmani
0009-0006-0709-2624
Algeria

Hassina Harkat
0000-0001-6181-1497
Algeria

Safa Chaira
0009-0008-2958-3103
Algeria

Nawal Achachi
0009-0000-2451-3968
Algeria

Publication Date

February 27, 2026

Submission Date

November 6, 2025

Acceptance Date

February 5, 2026

Published in Issue

Year 2026 Volume: 47 Number: 1

DOI

https://doi.org/10.17776/csj.1818332

IZ

https://izlik.org/JA92DG92SD

Cite

RIS / Bibtex

APA

Ben Moussa, M. T., Zeggada, C. E., Rahmani, A. M., Harkat, H., Chaira, S., & Achachi, N. (2026). The Hypoglycaemic Effect and Antioxidant and Anti-α-amylase Activity of the Hydroalcoholic Extract of Tamarix algeriensis G.Nicholson Tamaricaceae. Cumhuriyet Science Journal, 47(1), 55-64. https://doi.org/10.17776/csj.1818332