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The Hypoglycaemic Effect and Antioxidant and Anti-α-amylase Activity of the Hydroalcoholic Extract of Tamarix algeriensis G.Nicholson Tamaricaceae

Year 2026, Volume: 47 Issue: 1, 55 - 64, 27.02.2026

Mohammed Tahar Ben Moussa , Chihab Eddine Zeggada , Abdallah Mouadh Rahmani , Hassina Harkat , Safa Chaira , Nawal Achachi

https://doi.org/10.17776/csj.1818332
https://izlik.org/JA92DG92SD

Abstract

This study evaluated the hydroalcoholic extract of Tamarix algeriensis aerial parts' antihyperglycemic and antioxidant properties. In Batna, Algeria, the researchers gathered the plant's aerial parts, which they then macerated to create the extract. Numerous bioactive substances, such as flavonoids, saponins, polyphenols, steroids, terpenoids, tannins, and anthracene glycosides, were found during the initial phytochemical screening. Numerous techniques, such as ferric reducing power (FRAP), total antioxidant capacity (TAC), and DPPH free radical scavenging tests, were used to confirm the extract's strong antioxidant activity in vitro. Additionally, the extract demonstrated strong inhibitory activity against the enzyme α-amylase, which is essential for the breakdown of carbohydrates. Tamarix algeriensis extract significantly decreased blood glucose levels after a glucose load in in vivo tests on normoglycaemic mice, demonstrating a hypoglycaemic effect. These findings imply that Tamarix algeriensis hydroalcoholic extract may be a useful source of therapeutic compounds for the treatment of diabetes and oxidative stress.

Keywords

Antioxidant activity Diabetes Hypoglycemic activity Tamarix algeriensis α-amylase inhibition

Ethical Statement

IRB

Supporting Institution

faculty of medecine Annaba

Thanks

The writers acknowledge the Algerian Ministry of Higher Education and Scientific Research for their assistance inside the context of the PRFU project (approval n° B00L01UN052).

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There are 40 citations in total.

Details

Primary Language English
Subjects Plant Biochemistry
Journal Section Research Article
Authors

Mohammed Tahar Ben Moussa 0000-0002-0316-2887

Chihab Eddine Zeggada 0009-0002-0414-5904

Abdallah Mouadh Rahmani 0009-0006-0709-2624

Hassina Harkat 0000-0001-6181-1497

Safa Chaira 0009-0008-2958-3103

Nawal Achachi 0009-0000-2451-3968

Submission Date November 6, 2025
Acceptance Date February 5, 2026
Publication Date February 27, 2026
DOI https://doi.org/10.17776/csj.1818332
IZ https://izlik.org/JA92DG92SD
Published in Issue Year 2026 Volume: 47 Issue: 1

Cite

APA Ben Moussa, M. T., Zeggada, C. E., Rahmani, A. M., Harkat, H., Chaira, S., & Achachi, N. (2026). The Hypoglycaemic Effect and Antioxidant and Anti-α-amylase Activity of the Hydroalcoholic Extract of Tamarix algeriensis G.Nicholson Tamaricaceae. Cumhuriyet Science Journal, 47(1), 55-64. https://doi.org/10.17776/csj.1818332

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