Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters

Hayreddin Gezegen

doi:10.17776/csj.1341173

EN

Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters

Abstract

Chromene derivatives are among the natural compounds and they can also be easily obtained synthetically. They are one of the most commonly used skeletons in heterocyclic chemistry. Chromene derivatives are used in the cosmetic and pigment industries as well as having a wide spectrum of biological activity. Synthesis of chromene derivatives and their application areas is a current topic. In this study, it is aimed to synthesis and characterization of new chromene derivatives by catalysis of molecular iodine starting from 1,5-diol derivatives with chiral centers. In this context, 8 new 2,4-diaryloctahydro-2H-chromene derivatives were synthesized in high yields and their structure determinations were made by spectroscopic methods (1H-NMR, 13C-NMR, 2D-NMR, GCMS and FTIR) and their stereochemistry was determined.

Keywords

Supporting Institution

Gaziosmanpaşa Üniversitesi

Project Number

BAP-201194

References

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Details

Primary Language

English

Subjects

Organic Chemical Synthesis

Journal Section

Research Article

Authors

Hayreddin Gezegen ^*
0000-0003-3602-7400
Türkiye

Publication Date

December 28, 2023

Submission Date

August 11, 2023

Acceptance Date

November 13, 2023

Published in Issue

Year 2023 Volume: 44 Number: 4

DOI

https://doi.org/10.17776/csj.1341173

IZ

https://izlik.org/JA76AB86XJ

Cite

RIS / Bibtex

APA

Gezegen, H. (2023). Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. Cumhuriyet Science Journal, 44(4), 678-686. https://doi.org/10.17776/csj.1341173

Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters

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