Analysis of Carvedilol in Pharmaceutical Preparations by Spectrofluorometric Method

Bilal Yılmaz

doi:10.17776/csj.1092393

EN

Analysis of Carvedilol in Pharmaceutical Preparations by Spectrofluorometric Method

Abstract

The goal of this research is to develop a spectrofluorometric method for analyzing carvedilol in pharmaceutical preparations and apply this method to the formulations. The method’s calibration curve was plotted between 25 and 500 ng/mL. The mean calibration equation from six replicate experiments is y=1.8736x+7.7291. The correlation coefficient value was higher than 0.997 for the mean calibration curve. The trueness results were better than 2.09% and the precision results were less than 2.73% for carvedilol. The detection and quantitation limits were determined as 2.196 and 6.654 ng/mL, respectively. In addition, the method was used to study carvedilol in pharmaceutical preparations. The method had recovery values >98.4% for all samples in pharmaceutical preparations. The detection wavelength was optimized to maximize the sensitivity of the method. This method has good sensitivity with satisfactory results. Therefore, the method can be used in carvedilol analysis.

Keywords

Thanks

The author would like to thank Semih Yilmaz for expert advice on the use of English.

References

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Details

Primary Language

English

Subjects

Nonlinear Optics and Spectroscopy

Journal Section

Research Article

Authors

Bilal Yılmaz ^*
0000-0002-8574-7570
Türkiye

Publication Date

June 29, 2022

Submission Date

March 24, 2022

Acceptance Date

June 2, 2022

Published in Issue

Year 2022 Volume: 43 Number: 2

DOI

https://doi.org/10.17776/csj.1092393

IZ

https://izlik.org/JA92FH76MJ

Cite

RIS / Bibtex

APA

Yılmaz, B. (2022). Analysis of Carvedilol in Pharmaceutical Preparations by Spectrofluorometric Method. Cumhuriyet Science Journal, 43(2), 188-192. https://doi.org/10.17776/csj.1092393

Cited By

Inhibition of protein glycation by vasodilatory β-blockers – In vitro studies and in silico analyses

Biomedicine & Pharmacotherapy

https://doi.org/10.1016/j.biopha.2025.117976

Öz

Analysis of Carvedilol in Pharmaceutical Preparations by Spectrofluorometric Method

Abstract

Keywords

Thanks

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Inhibition of protein glycation by vasodilatory β-blockers – In vitro studies and in silico analyses