Araştırma Makalesi
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Yıl 2022, Cilt: 43 Sayı: 4, 708 - 715, 27.12.2022

İbrahim Etem Gül Sinan Kuday

https://doi.org/10.17776/csj.1152691

Öz

Kaynakça

  • [1] Munier F., Vervey J., Pica A., (Eds). New Developments İn External Beam Radiotherapy for Retinoblastoma: From Lens To Normal Tissue-Sparing Techniques, Clinical Experiments Ophthalmology, 36 (2008) 78-89.
  • [2] Lee T., Bilton D., Famiglietti R., (Eds). Treatment Planning With Protons For Pediatric Retinoblastoma, Medulloblastoma, And Pelvic Sarcoma: How Do Protons Compare With Other Conformal Techniques, Internation Journal Radiation Oncology Biology Physics, 36 (2005) 362–372.
  • [3] M P Mehta, Proton Therapy Predictions for the Next Decade, Miami Cancer Institute, July 06, 2020.
  • [4] Paganetti H. (Eds). Proton Therapy Physics. 1 nd ed. Boston, (2012) 516-544.
  • [5] Geant 4 A Sımılatıon Toolkıt Available at: https://geant4.web.cern.ch?, statfacts_page=corp. Retrieved August 17, 2022.
  • [6] GateOpenGate Collaboration Available at: https://opengate.readthedocs.io/en/latest/introduction /html? , statfacts_page=corp. Retrieved August 17, 2022.
  • [7] Başmak H., Gözün Anatomisi ve Fizyolojisi. 1 nd ed. Eskişehir, (2005) 12-44.
  • [8] Valentın J.,(Eds). Internatıon Commıssıon On Radıologıcal Protectıon Basic Anatomical and Physiological Data for Use in Radiological Protection Reference Values, ICRP Publication 89, 32 (3-4) (2002) 217-220
  • [9] Allisy A. (Eds). Reports of the International Commission on Radiation Units and Measurements, ICRU Publication 46, 24 (1) (1992) 19-24
  • [10] Stafford S., Pollock B., Leavitt J., A Study Of The Radiation Tolerance Of The Optic Nerves And Chiasm After Stereotactic Radiosurgery, International Journal Radiation Oncology Biology Physics, 55, (2003) 77-81.
  • [11] Vincent Gregoire , Wilfried De Neve , Avraham Eisbruch , Nancy Lee , Danielle Van den Weyngaert , Dirk Van Gestel, Intensity-Modulated Radiation Therapy For Head And Neck Carcinoma, Oncologist, 12 (2007) 555–564.
  • [12] Haegin Hana , Yeon Soo Yeoma , Thang Tat Nguyena , Chansoo Choia , Hanjin Leea , Bangho Shina , Chan Hyeong Kima , Development of Detailed Eye Models for Pediatric Phantoms, Transactions of the Korean Nuclear Society Autumn Meeting Gyeongju, 103 (2017) 6.
  • [13] Steven Nguyen , Julian Sison , Marjorie Jones , Jesse L Berry , Jonathan W Kim , A Linn Murphree , Vanessa Salinas , Arthur J Olch , Eric L Chang , Kenneth K Wong, Lens Dose-Response Prediction Modeling and Cataract Incidence in Patients With Retinoblastoma After Lens-Sparing or Whole-Eye Radiation Therapy, Internation Journal Radiation Oncology Biology Physics, 103 (5) (2019) 1143-1150.
  • [14] Jones B., Errington D., Proton Beam Radiotherapy, British Journal Of Radiology,73 (2000) 802-805.
  • [15] Frances C., Charlwood,A., H., Aitkenhead,Ranald I. Mackay , A Monte Carlo Study On The Collimation Of Pencil Beam Scanning Proton Therapy Beams, Medical Phys.,43 (2016) 1462-1472
  • [16] Baldacci F., Mittone A., Bravin A., (Eds). A Track Length Estimator Method For Dose Calculations İn Low-Energy X-Ray İrradiations, Implementation, Properties And Performance, Zeitschrift Für Medizinische Physik, 25 (2015) 36-47.
  • [17] Smekens F.,Freud N., (Eds). Simulation Of Dose Deposition İn Stereotactic Synchrotron Radiation Therapy, A Fast Approach Combining Monte Carlo And Deterministic Algorithms, 54 (2009) 4671-4685
  • [18] Stewart, F., Akleyev A., Hauer J., (Eds). ICRP Statement on Tissue Reactions and Early and late Effects of Radiation in Normal Tissues and Organs Threshold Doses for Tissue Reactions, ICRP Publication, 41 (1-2) (2012) 293-300.

Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations

Yıl 2022, Cilt: 43 Sayı: 4, 708 - 715, 27.12.2022

İbrahim Etem Gül Sinan Kuday

https://doi.org/10.17776/csj.1152691

Öz

One of the most frequent children tumors in the area around the eyes is defined as retinoblastoma. Proton radiotherapy treatment is a particularly effective type of radiation therapy due to the prolonged survival rates of children with childhood cancers such as retinablastoma, continued growth of nearby organs and tissues, low radiation dose restriction of vision-related tissues and systems of these tissues. In this study, a geometry phantom including eyeball, lens, lacrimal gland, optic nerve, optic chiasm, retina, cancer, cornea and bone structures was modeled with Monte Carlo simulation tool GATE (vGATE 9.0). With this simulation, the doses absorbed by the tissues were calculated using the DoseActor and TLEDoseActor algorithms. Secondary doses were determined by the TLEDoseActor algorithm. Determination of secondary radiations is important because of the low radiation dose limit of tissues and systems that affect vision. The best treatment results were tried to be obtained by giving the beam thickness of the radiation used in our study, 4 different angles towards the target and different energies. These results show that it can be helpful in calculating a treatment plan for proton therapy in clinical practice.

Anahtar Kelimeler

GATE DoseActor TLEDoseActor Proton therapy Retinablastoma Radiotherapy.

Kaynakça

  • [1] Munier F., Vervey J., Pica A., (Eds). New Developments İn External Beam Radiotherapy for Retinoblastoma: From Lens To Normal Tissue-Sparing Techniques, Clinical Experiments Ophthalmology, 36 (2008) 78-89.
  • [2] Lee T., Bilton D., Famiglietti R., (Eds). Treatment Planning With Protons For Pediatric Retinoblastoma, Medulloblastoma, And Pelvic Sarcoma: How Do Protons Compare With Other Conformal Techniques, Internation Journal Radiation Oncology Biology Physics, 36 (2005) 362–372.
  • [3] M P Mehta, Proton Therapy Predictions for the Next Decade, Miami Cancer Institute, July 06, 2020.
  • [4] Paganetti H. (Eds). Proton Therapy Physics. 1 nd ed. Boston, (2012) 516-544.
  • [5] Geant 4 A Sımılatıon Toolkıt Available at: https://geant4.web.cern.ch?, statfacts_page=corp. Retrieved August 17, 2022.
  • [6] GateOpenGate Collaboration Available at: https://opengate.readthedocs.io/en/latest/introduction /html? , statfacts_page=corp. Retrieved August 17, 2022.
  • [7] Başmak H., Gözün Anatomisi ve Fizyolojisi. 1 nd ed. Eskişehir, (2005) 12-44.
  • [8] Valentın J.,(Eds). Internatıon Commıssıon On Radıologıcal Protectıon Basic Anatomical and Physiological Data for Use in Radiological Protection Reference Values, ICRP Publication 89, 32 (3-4) (2002) 217-220
  • [9] Allisy A. (Eds). Reports of the International Commission on Radiation Units and Measurements, ICRU Publication 46, 24 (1) (1992) 19-24
  • [10] Stafford S., Pollock B., Leavitt J., A Study Of The Radiation Tolerance Of The Optic Nerves And Chiasm After Stereotactic Radiosurgery, International Journal Radiation Oncology Biology Physics, 55, (2003) 77-81.
  • [11] Vincent Gregoire , Wilfried De Neve , Avraham Eisbruch , Nancy Lee , Danielle Van den Weyngaert , Dirk Van Gestel, Intensity-Modulated Radiation Therapy For Head And Neck Carcinoma, Oncologist, 12 (2007) 555–564.
  • [12] Haegin Hana , Yeon Soo Yeoma , Thang Tat Nguyena , Chansoo Choia , Hanjin Leea , Bangho Shina , Chan Hyeong Kima , Development of Detailed Eye Models for Pediatric Phantoms, Transactions of the Korean Nuclear Society Autumn Meeting Gyeongju, 103 (2017) 6.
  • [13] Steven Nguyen , Julian Sison , Marjorie Jones , Jesse L Berry , Jonathan W Kim , A Linn Murphree , Vanessa Salinas , Arthur J Olch , Eric L Chang , Kenneth K Wong, Lens Dose-Response Prediction Modeling and Cataract Incidence in Patients With Retinoblastoma After Lens-Sparing or Whole-Eye Radiation Therapy, Internation Journal Radiation Oncology Biology Physics, 103 (5) (2019) 1143-1150.
  • [14] Jones B., Errington D., Proton Beam Radiotherapy, British Journal Of Radiology,73 (2000) 802-805.
  • [15] Frances C., Charlwood,A., H., Aitkenhead,Ranald I. Mackay , A Monte Carlo Study On The Collimation Of Pencil Beam Scanning Proton Therapy Beams, Medical Phys.,43 (2016) 1462-1472
  • [16] Baldacci F., Mittone A., Bravin A., (Eds). A Track Length Estimator Method For Dose Calculations İn Low-Energy X-Ray İrradiations, Implementation, Properties And Performance, Zeitschrift Für Medizinische Physik, 25 (2015) 36-47.
  • [17] Smekens F.,Freud N., (Eds). Simulation Of Dose Deposition İn Stereotactic Synchrotron Radiation Therapy, A Fast Approach Combining Monte Carlo And Deterministic Algorithms, 54 (2009) 4671-4685
  • [18] Stewart, F., Akleyev A., Hauer J., (Eds). ICRP Statement on Tissue Reactions and Early and late Effects of Radiation in Normal Tissues and Organs Threshold Doses for Tissue Reactions, ICRP Publication, 41 (1-2) (2012) 293-300.
Toplam 18 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klasik Fizik (Diğer)
Bölüm Natural Sciences
Yazarlar

İbrahim Etem Gül 0000-0001-6972-3635

Sinan Kuday 0000-0002-0116-5494

Yayımlanma Tarihi 27 Aralık 2022
Gönderilme Tarihi 3 Ağustos 2022
Kabul Tarihi 25 Ağustos 2022
Yayımlandığı Sayı Yıl 2022Cilt: 43 Sayı: 4

Kaynak Göster

APA Gül, İ. E., & Kuday, S. (2022). Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations. Cumhuriyet Science Journal, 43(4), 708-715. https://doi.org/10.17776/csj.1152691
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