Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations

İbrahim Etem Gül; Sinan Kuday

doi:10.17776/csj.1152691

EN

Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations

Abstract

One of the most frequent children tumors in the area around the eyes is defined as retinoblastoma. Proton radiotherapy treatment is a particularly effective type of radiation therapy due to the prolonged survival rates of children with childhood cancers such as retinablastoma, continued growth of nearby organs and tissues, low radiation dose restriction of vision-related tissues and systems of these tissues. In this study, a geometry phantom including eyeball, lens, lacrimal gland, optic nerve, optic chiasm, retina, cancer, cornea and bone structures was modeled with Monte Carlo simulation tool GATE (vGATE 9.0). With this simulation, the doses absorbed by the tissues were calculated using the DoseActor and TLEDoseActor algorithms. Secondary doses were determined by the TLEDoseActor algorithm. Determination of secondary radiations is important because of the low radiation dose limit of tissues and systems that affect vision. The best treatment results were tried to be obtained by giving the beam thickness of the radiation used in our study, 4 different angles towards the target and different energies. These results show that it can be helpful in calculating a treatment plan for proton therapy in clinical practice.

Keywords

References

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Details

Primary Language

English

Subjects

Classical Physics (Other)

Journal Section

Research Article

Authors

İbrahim Etem Gül ^*
0000-0001-6972-3635
Türkiye

Sinan Kuday
0000-0002-0116-5494
Türkiye

Publication Date

December 27, 2022

Submission Date

August 3, 2022

Acceptance Date

August 25, 2022

Published in Issue

Year 2022 Volume: 43 Number: 4

DOI

https://doi.org/10.17776/csj.1152691

IZ

https://izlik.org/JA59LS38RU

Cite

RIS / Bibtex

APA

Gül, İ. E., & Kuday, S. (2022). Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations. Cumhuriyet Science Journal, 43(4), 708-715. https://doi.org/10.17776/csj.1152691

AMA

1.Gül İE, Kuday S. Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations. CSJ. 2022;43(4):708-715. doi:10.17776/csj.1152691

Chicago

Gül, İbrahim Etem, and Sinan Kuday. 2022. “Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations”. Cumhuriyet Science Journal 43 (4): 708-15. https://doi.org/10.17776/csj.1152691.

EndNote

Gül İE, Kuday S (December 1, 2022) Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations. Cumhuriyet Science Journal 43 4 708–715.

IEEE

[1]İ. E. Gül and S. Kuday, “Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations”, CSJ, vol. 43, no. 4, pp. 708–715, Dec. 2022, doi: 10.17776/csj.1152691.

ISNAD

Gül, İbrahim Etem - Kuday, Sinan. “Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations”. Cumhuriyet Science Journal 43/4 (December 1, 2022): 708-715. https://doi.org/10.17776/csj.1152691.

JAMA

1.Gül İE, Kuday S. Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations. CSJ. 2022;43:708–715.

MLA

Gül, İbrahim Etem, and Sinan Kuday. “Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations”. Cumhuriyet Science Journal, vol. 43, no. 4, Dec. 2022, pp. 708-15, doi:10.17776/csj.1152691.

Vancouver

1.İbrahim Etem Gül, Sinan Kuday. Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations. CSJ. 2022 Dec. 1;43(4):708-15. doi:10.17776/csj.1152691