Electrochemical Investigation of Carbon Nanotube Modified Surfaces Based on Ferricyanide and Guanine Signals for DNA Biosensor Applications

Dilşat Arıksoysal

doi:10.17776/csj.441382

TR EN

Electrochemical Investigation of Carbon Nanotube Modified Surfaces Based on Ferricyanide and Guanine Signals for DNA Biosensor Applications

Abstract

This study was designed to investigate the performance of carbon nanotubes (CNT) modified carbon paste and carbon printed electrodes (SPE) produced in laboratory conditions. The effect of carbon nanotube use on signal enrichment was determined by using cyclic voltammetry (CV), square wave voltammetry (SWV) or differential pulse voltammetry (DPV) techniques based on potassium ferricyanide/ ferrocyanide or guanine signal. The application of different activation procedures to the electrode surface such as chemical (H₂SO₄, acetone, N,N-Dimethylformamide or NaOH) or electrochemical (different potential applications) were presented in this study. It was observed that the activation procedure applied to the nanotube modified electrode has strong effects on signal enrichment. From these procedures it was determined that the guanine signal obtained in activation with NaOH increased about 62-fold. It was also found that different nanotube species gave different responses to the activation processes. The optimum conditions of the nanotube-based biosensor were also presented.

Keywords

Electrochemical techniques,DNA,biosensor,carbon nanotubes,screen printed electrode(SPE),Nucleic Acid Hybridization

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Dilşat Arıksoysal ^*
0000-0002-8471-5665
Türkiye

Publication Date

March 22, 2019

Submission Date

July 12, 2018

Acceptance Date

March 21, 2019

Published in Issue

Year 2019 Volume: 40 Number: 1

DOI

https://doi.org/10.17776/csj.441382

IZ

https://izlik.org/JA48XR35RC

Cite

RIS / Bibtex

APA

Arıksoysal, D. (2019). Electrochemical Investigation of Carbon Nanotube Modified Surfaces Based on Ferricyanide and Guanine Signals for DNA Biosensor Applications. Cumhuriyet Science Journal, 40(1), 11-23. https://doi.org/10.17776/csj.441382

Cited By

Does Favipiravir interact with DNA? Design of electrochemical DNA nanobiosensor to investigate the interaction between DNA and Favipiravir used in the treatment of COVID-19

Talanta

https://doi.org/10.1016/j.talanta.2025.128084

Electrochemical Investigation of Carbon Nanotube Modified Surfaces Based on Ferricyanide and Guanine Signals for DNA Biosensor Applications

DNA Biyosensör Uygulamaları İçin Karbon Nanotüp Modifiye Yüzeylerin Ferrisiyanür ve Guanin Sinyallerine Dayalı Olarak Elektrokimyasal İncelenmesi

Öz

Anahtar Kelimeler

Electrochemical Investigation of Carbon Nanotube Modified Surfaces Based on Ferricyanide and Guanine Signals for DNA Biosensor Applications

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Does Favipiravir interact with DNA? Design of electrochemical DNA nanobiosensor to investigate the interaction between DNA and Favipiravir used in the treatment of COVID-19