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Supramolecular Solvent Liquid Phase Microextraction of Voriconazole İn Pharmaceutical and Environmental Samples With High Performance Liquid Chromatography Detection

Year 2024, Volume: 45 Issue: 3, 490 - 495, 30.09.2024

Erkan Yılmaz , Gülnihal Yıldız

https://doi.org/10.17776/csj.1455893

Abstract

In this study, a new analytical method based on the supramolecular solvent liquid phase microextraction (Ss-LPME) and HPLC was developed for the analysis of voriconazole as an active drug in the class of antifungals with a wide spectrum of action at trace levels. Nano/micro sized supramolecular phase formed in 1-decanol, tetrahydrofuran and aqueous environment was used as extraction agent for separation and preconcentration of trace level of voriconazole. For the optimization of the Ss-LPME method, important analytical parameters such as the effect of sample solution pH, volume of 1-decanol, amount of THF, ultrasounic irridation time, centrifugation time and sample solution volume on the extraction efficiency were evaluated. Optimal conditions of the Ss-LPME; pH: 8, 1-decanol volume: 200 µL, THF volume: 300 µL, ultrasounic irridation time:10 min and centrifugation time: 8 min. For the developed Ss-LPME/HPLC procedure, the limit of detection (LOD), limit of quantification (LOQ) and enhancement factor (EF) were found 2.7 µg·L-1, 8.8 µg·L-1 and 36, respectively. The Ss-LPME/HPLC procedure was applied to waste water, lake water and drug samples. The fact that recovery values ranging from 100% to 108.5% were obtained for these real samples proved that this method can be used successfully in the matrix environments studied

Keywords

Voriconazole anaylsis Supramolecular solvent liquid phase microextraction Preconcentration

References

  • [1] Alarfaj N.A., Maha F. E., Electrochemical Sensors For Direct Potentiometric Determination of Voriconazole in Pharmaceutical Dosage Forms and Biological Fluids., International Journal of Physical Sciences, 7(9) (2012) 1403-1411.
  • [2] Liu J., Fan W., Lv X., Wang C., Rapid Quantitative Detection of Voriconazole in Human Plasma Using Surface-Enhanced Raman Scattering, ACS omega, 7 (51) (2022) 47634-47641.
  • [3] Gunawan U., Ibrahim S., Ivansyah A. L., Damayanti S., Insights Into the Selective Imprinted Polymer of Voriconazole from Host-Guest Interaction Perspective., Journal of Molecular Liquids, 383 (2023) 122130.
  • [4] Zhao Y. M., Tang G. M., Wang Y. T., Cui Y. Z., Synthesis, Spectroscopic Studies, Antimicrobial Activity, and Crystal Structure of a Zn (II) Complex Based on Voriconazole, Journal of Coordination Chemistry, 70 (2) (2017) 189-200.
  • [5] Bashir K., Chen G., Han J., Shu H., Cui X., Wang L., Fu Q., Preparation of Magnetic Metal Organic Framework and Development of Solid Phase Extraction Method for Simultaneous Determination of Fluconazole and Voriconazole in Rat Plasma Samples by HPLC, Journal of Chromatography B, 1152 (2020) 122201.
  • [6] Chawla P. K., Dherai A. J., Ashavaid T. F., Plasma Voriconazole Estimation by HPLC, Indian Journal of Clinical Biochemistry, 31 (2016) 209-214.
  • [7] Srinubabu G., Raju C. A., Sarath N., Kumar P. K., Rao J. S., Development and Validation of a HPLC Method for the Determination of Voriconazole in Pharmaceutical Formulation Using an Experimental Design, Talanta, 71(3) (2007) 1424-1429.
  • [8] Liu J., Fan W., Lv X., Wang C., Rapid Quantitative Detection of Voriconazole in Human Plasma Using Surface-Enhanced Raman Scattering, ACS omega, 7(51) (2022) 47634-47641.
  • [9] Bashir K., Chen G., Han J., Shu H., Cui X., Wang L.,Fu Q., Preparation of Magnetic Metal Organic Framework and Development of Solid Phase Extraction Method for Simultaneous Determination of Fluconazole and Voriconazole in Rat Plasma Samples by HPLC, Journal of Chromatography B, 1152 (2020) 122201.
  • [10] Michael C., Teichert J., Preiss R., Determination of Voriconazole in Human Plasma and Saliva Using High-Performance Liquid Chromatography with Fluorescence Detection, Journal of Chromatography B, 865(1-2) (2008) 74-80.
  • [11] Sarafraz-Yazdi A., AmiriA., Liquid-Phase Microextraction, TrAC Trends in Analytical Chemistry, 29(1) (2010) 1-14.
  • [12] Psillakis E., Kalogerakis N., Developments in Liquid-Phase Microextraction, TrAC Trends in Analytical Chemistry, 22(9) (2003) 565-574.
  • [13] Santos L. B., Assis R. S., Barreto J. A., Bezerra M. A., Novaes C. G., Lemos V.A., Deep Eutectic Solvents in Liquid-Phase Microextraction: Contribution to Green Chemistry, TrAC Trends in Analytical Chemistry, 146 (2022) 116478.
  • [14] Arain M. B., Yilmaz E., Soylak M., Deep Eutectic Solvent Based Ultrasonic Assisted Liquid Phase Microextraction for the FAAS Determination of Cobalt, Journal of Molecular Liquids, 224 (2016) 538-543.
  • [15] Rezaei F., Yamini Y., Moradi M., Daraei B., Supramolecular Solvent-Based Hollow Fiber Liquid Phase Microextraction of Benzodiazepines, Analytica Chimica Acta, 804 (2013) 135-142.
  • [16] Moradi M., Yamini Y., Feizi N., Development and Challenges of Supramolecular Solvents in Liquid-Based Microextraction Methods, TrAC Trends in Analytical Chemistry, 138 (2021) 116231
  • [17] Zohrabi P., Shamsipur M., Hashemi M., Hashemi B., Liquid-Phase Microextraction of Organophosphorus Pesticides Using Supramolecular Solvent as a Carrier for Ferrofluid, Talanta, 160 (2016) 340-346.
  • [18] Mirzajani R., Kardani F., Ramezani Z., Preparation and characterization of magnetic metal–organic framework nanocomposite as solid-phase microextraction fibers coupled with high-performance liquid chromatography for determination of non-steroidal anti-inflammatory drugs in biological fluids and tablet formulation samples. Microchemical Journal, 144 (2019) 270-284.
  • [19] Valıdatıon of Analytıcal Procedures: Text And Methodology Q2(R1), Available at: https://database.ich.org/sites/default/files/Q2%28R1%29%20Guideline.pdf. Retrieved March, 2024.

Year 2024, Volume: 45 Issue: 3, 490 - 495, 30.09.2024

Erkan Yılmaz , Gülnihal Yıldız

https://doi.org/10.17776/csj.1455893

Abstract

References

  • [1] Alarfaj N.A., Maha F. E., Electrochemical Sensors For Direct Potentiometric Determination of Voriconazole in Pharmaceutical Dosage Forms and Biological Fluids., International Journal of Physical Sciences, 7(9) (2012) 1403-1411.
  • [2] Liu J., Fan W., Lv X., Wang C., Rapid Quantitative Detection of Voriconazole in Human Plasma Using Surface-Enhanced Raman Scattering, ACS omega, 7 (51) (2022) 47634-47641.
  • [3] Gunawan U., Ibrahim S., Ivansyah A. L., Damayanti S., Insights Into the Selective Imprinted Polymer of Voriconazole from Host-Guest Interaction Perspective., Journal of Molecular Liquids, 383 (2023) 122130.
  • [4] Zhao Y. M., Tang G. M., Wang Y. T., Cui Y. Z., Synthesis, Spectroscopic Studies, Antimicrobial Activity, and Crystal Structure of a Zn (II) Complex Based on Voriconazole, Journal of Coordination Chemistry, 70 (2) (2017) 189-200.
  • [5] Bashir K., Chen G., Han J., Shu H., Cui X., Wang L., Fu Q., Preparation of Magnetic Metal Organic Framework and Development of Solid Phase Extraction Method for Simultaneous Determination of Fluconazole and Voriconazole in Rat Plasma Samples by HPLC, Journal of Chromatography B, 1152 (2020) 122201.
  • [6] Chawla P. K., Dherai A. J., Ashavaid T. F., Plasma Voriconazole Estimation by HPLC, Indian Journal of Clinical Biochemistry, 31 (2016) 209-214.
  • [7] Srinubabu G., Raju C. A., Sarath N., Kumar P. K., Rao J. S., Development and Validation of a HPLC Method for the Determination of Voriconazole in Pharmaceutical Formulation Using an Experimental Design, Talanta, 71(3) (2007) 1424-1429.
  • [8] Liu J., Fan W., Lv X., Wang C., Rapid Quantitative Detection of Voriconazole in Human Plasma Using Surface-Enhanced Raman Scattering, ACS omega, 7(51) (2022) 47634-47641.
  • [9] Bashir K., Chen G., Han J., Shu H., Cui X., Wang L.,Fu Q., Preparation of Magnetic Metal Organic Framework and Development of Solid Phase Extraction Method for Simultaneous Determination of Fluconazole and Voriconazole in Rat Plasma Samples by HPLC, Journal of Chromatography B, 1152 (2020) 122201.
  • [10] Michael C., Teichert J., Preiss R., Determination of Voriconazole in Human Plasma and Saliva Using High-Performance Liquid Chromatography with Fluorescence Detection, Journal of Chromatography B, 865(1-2) (2008) 74-80.
  • [11] Sarafraz-Yazdi A., AmiriA., Liquid-Phase Microextraction, TrAC Trends in Analytical Chemistry, 29(1) (2010) 1-14.
  • [12] Psillakis E., Kalogerakis N., Developments in Liquid-Phase Microextraction, TrAC Trends in Analytical Chemistry, 22(9) (2003) 565-574.
  • [13] Santos L. B., Assis R. S., Barreto J. A., Bezerra M. A., Novaes C. G., Lemos V.A., Deep Eutectic Solvents in Liquid-Phase Microextraction: Contribution to Green Chemistry, TrAC Trends in Analytical Chemistry, 146 (2022) 116478.
  • [14] Arain M. B., Yilmaz E., Soylak M., Deep Eutectic Solvent Based Ultrasonic Assisted Liquid Phase Microextraction for the FAAS Determination of Cobalt, Journal of Molecular Liquids, 224 (2016) 538-543.
  • [15] Rezaei F., Yamini Y., Moradi M., Daraei B., Supramolecular Solvent-Based Hollow Fiber Liquid Phase Microextraction of Benzodiazepines, Analytica Chimica Acta, 804 (2013) 135-142.
  • [16] Moradi M., Yamini Y., Feizi N., Development and Challenges of Supramolecular Solvents in Liquid-Based Microextraction Methods, TrAC Trends in Analytical Chemistry, 138 (2021) 116231
  • [17] Zohrabi P., Shamsipur M., Hashemi M., Hashemi B., Liquid-Phase Microextraction of Organophosphorus Pesticides Using Supramolecular Solvent as a Carrier for Ferrofluid, Talanta, 160 (2016) 340-346.
  • [18] Mirzajani R., Kardani F., Ramezani Z., Preparation and characterization of magnetic metal–organic framework nanocomposite as solid-phase microextraction fibers coupled with high-performance liquid chromatography for determination of non-steroidal anti-inflammatory drugs in biological fluids and tablet formulation samples. Microchemical Journal, 144 (2019) 270-284.
  • [19] Valıdatıon of Analytıcal Procedures: Text And Methodology Q2(R1), Available at: https://database.ich.org/sites/default/files/Q2%28R1%29%20Guideline.pdf. Retrieved March, 2024.
There are 19 citations in total.

Details

Primary Language English
Subjects Instrumental Methods, Separation Science, Analytical Chemistry (Other)
Journal Section Natural Sciences
Authors

Erkan Yılmaz 0000-0001-8962-3199

Gülnihal Yıldız 0009-0002-8418-3846

Publication Date September 30, 2024
Submission Date March 20, 2024
Acceptance Date August 14, 2024
Published in Issue Year 2024Volume: 45 Issue: 3

Cite

APA Yılmaz, E., & Yıldız, G. (2024). Supramolecular Solvent Liquid Phase Microextraction of Voriconazole İn Pharmaceutical and Environmental Samples With High Performance Liquid Chromatography Detection. Cumhuriyet Science Journal, 45(3), 490-495. https://doi.org/10.17776/csj.1455893
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