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Year 2021, Volume: 42 Issue: 3, 629 - 637, 24.09.2021

Songül Ulusoy

https://doi.org/10.17776/csj.937421

Abstract

References

  • [1] Kurzawa M., Determination of quercetin and rutin in selected herbs and pharmaceutical preparations, Anal. Lett., 43 (2010) 993–1002.
  • [2] Kanberoglu G.S., Yilmaz E., Soylak M., Application of deep eutectic solvent in ultrasound-assisted emulsification microextraction of quercetin from some fruits and vegetables, J. Mol. Liq., 279 (2019) 571–577.
  • [3] Zhiltsova E.P., Ibatullina M.R., Lukashenko S.S., Kutyreva M.P., Zakharovac L.Y., Spectrophotometric study of quercetin in metallomicellar solutions of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2] octane bromide complex with copper dibromide, J. Mol. Liq., 249 (2018) 716–722.
  • [4] Ranjbar Banforuzi S., Hadjmohammadi M.R., Two-phase hollow fiber-liquid microextraction based on reverse micelle for the determination of quercetin in human plasma and vegetables samples, Talanta, 173 (2017) 14–21. A. Murakami H., Ashida J., Terao, Multitargeted cancer prevention by quercetin, Cancer Lett., 269 (2008) 315–325.
  • [5] Boots A.W., Haenen G.R.M.M., Bast A., Health effects of quercetin: From antioxidant to nutraceutical, Eur. J. Pharmacol., 585 (2008) 325–337.
  • [6] Lobo V., Patil A., Phatak A., Chandra N., Free radicals, antioxidants and functional foods: Impact on human health, Pharmacogn. Rev., 4 (2010) 118.
  • [7] Jiang H., Engelhardt U.H., Thräne C., Maiwald B., Stark J., Determination of flavonol glycosides in green tea, oolong tea and black tea by UHPLC compared to HPLC, Food Chem., 183 (2015) 30–35.
  • [8] Xiao P., Zhao F., Zeng B., Voltammetric determination of quercetin at a multi-walled carbon nanotubes paste electrode, Microchem. J., 85 (2007) 244–249.
  • [9] Chafer A., Pascual M.C., Salvador A., Berna A., Supercritical fluid extraction and HPLC determination of relevant polyphenolic compounds in grape skin, J. Sep. Sci., 28 (2005) 2050–2056.
  • [10] Wu H., Chen M., Fan Y., Elsebaei F., Zhu Y., Determination of rutin and quercetin in Chinese herbal medicine by ionic liquid-based pressurized liquid extraction-liquid chromatography- chemiluminescence detection, Talanta, 88 (2012) 222–229.
  • [11] Ranjbari E., Biparva P., Hadjmohammadi M.R., Utilization of inverted dispersive liquid-liquid microextraction followed by HPLC-UV as a sensitive and efficient method for the extraction and determination of quercetin in honey and biological samples, Talanta, 89 (2012) 117–123.
  • [12] Ulusoy H.İ., Applications of magnetic nanoparticles for the selective extraction of trace species from a complex matrix, 1st ed., New York: Nova Scientific Publishers, (2017).
  • [13] Ulusoy S., Yilmaz E., Erbas Z., Ulusoy H.I., Soylak M., Trace analysis of quercetin in tea samples by HPLC-DAD system by means of a new nanocomposite including magnetic core-shell, Sep. Sci. Technol., (2019).
  • [14] Şenol Z.M., Şimşek S., Ulusoy H.İ., Mahmood A., Kaya S., Insight from adsorption properties of Xylidyl Blue embedded hydrogel for effective removal of uranyl: Experimental and theoretical approaches, Polym. Test., (2020).
  • [15] Memon Z.M., Yilmaz E., Soylak M., Multivariate statistical design optimization for ultrasonic-assisted restricted access supramolecular solvent-based liquid phase microextraction of quercetin in food samples, J. Iran. Chem. Soc., 14 (2017) 2521–2528.
  • [16] Karaca E., Ulusoy S., Morgül U., Ulusoy H.İ., Development of Analytical Method for Sensitive Determination of Streptozotocin based on Solid Phase Extraction, Cumhur. Sci. J., 41 (2020) 826–831.
  • [17] Ulusoy H.I., Şimşek S., Removal of uranyl ions in aquatic mediums by using a new material: Gallocyanine grafted hydrogel, J. Hazard. Mater., 255 (2013) 397-405.
  • [18] Şimşek S., Şenol Z.M., Ulusoy H.İ., Synthesis and characterization of a composite polymeric material including chelating agent for adsorption of uranyl ions, J. Hazard. Mater., 338 (2017) 437–446.
  • [19] Ulusoy H.T., Şimşek S., Removal of uranyl ions in aquatic mediums by using a new material: Gallocyanine grafted hydrogel, J. Hazard. Mater. 254–255 (2013) 397-405.
  • [20] Soylak M., Ozdemir B., Yilmaz E., An environmentally friendly and novel amine-based liquid phase microextraction of quercetin in food samples prior to its determination by UV–vis spectrophotometry, Spectrochim. Acta - Part A Mol. Biomol. Spectrosc., 243 (2020) 118806.

Synthesis of new solid phase sorbent for sensitive spectrophotometric determination of Quercetin

Year 2021, Volume: 42 Issue: 3, 629 - 637, 24.09.2021

Songül Ulusoy

https://doi.org/10.17776/csj.937421

Abstract

Sensitive and easy applicable analysis of Quercetin molecules was executed whereby solid phase extraction (SPE) and molecular spectrophotometric determination. For the determination of quercetin, an accurate, economical, time-saving and a new environmentally friendly method has been developed with a simple spectrophotometer device available in every laboratory. As a solid-phase sorbent, a new polymer nanocomposite has been synthesized and characterized by Fouirer Transform Infrared Spectroscopy (FT-IR) and Scanned Electron Microscopy (SEM). Experimental solid phase extraction variables have been investigated and optimized step by step, such as pH, adsorption time and desorption conditions, etc. According to optimization results, desorption of quercetin molecules was carried out by 2-propanol solvent and absorbance of eluent solutions were measured as systematic at 255 nm and at 370 nm. However, the best results were obtained at 370 nm wavelength. Therefore, all measurements were made at 370 nm. (LOD) means that the detection limit and (LOQ), the quantitation limit values for quercetin were calculated as 5.97 ng mL-1and 17.91 ng mL-1, respectively. Standard addition and recovery experiments were performed as an indicator of the accuracy of the method. The method developed was effectively conducted to model solutions.

Keywords

Quercetin Solid phase extraction Polymeric adsorbent Analytical method development

References

  • [1] Kurzawa M., Determination of quercetin and rutin in selected herbs and pharmaceutical preparations, Anal. Lett., 43 (2010) 993–1002.
  • [2] Kanberoglu G.S., Yilmaz E., Soylak M., Application of deep eutectic solvent in ultrasound-assisted emulsification microextraction of quercetin from some fruits and vegetables, J. Mol. Liq., 279 (2019) 571–577.
  • [3] Zhiltsova E.P., Ibatullina M.R., Lukashenko S.S., Kutyreva M.P., Zakharovac L.Y., Spectrophotometric study of quercetin in metallomicellar solutions of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2] octane bromide complex with copper dibromide, J. Mol. Liq., 249 (2018) 716–722.
  • [4] Ranjbar Banforuzi S., Hadjmohammadi M.R., Two-phase hollow fiber-liquid microextraction based on reverse micelle for the determination of quercetin in human plasma and vegetables samples, Talanta, 173 (2017) 14–21. A. Murakami H., Ashida J., Terao, Multitargeted cancer prevention by quercetin, Cancer Lett., 269 (2008) 315–325.
  • [5] Boots A.W., Haenen G.R.M.M., Bast A., Health effects of quercetin: From antioxidant to nutraceutical, Eur. J. Pharmacol., 585 (2008) 325–337.
  • [6] Lobo V., Patil A., Phatak A., Chandra N., Free radicals, antioxidants and functional foods: Impact on human health, Pharmacogn. Rev., 4 (2010) 118.
  • [7] Jiang H., Engelhardt U.H., Thräne C., Maiwald B., Stark J., Determination of flavonol glycosides in green tea, oolong tea and black tea by UHPLC compared to HPLC, Food Chem., 183 (2015) 30–35.
  • [8] Xiao P., Zhao F., Zeng B., Voltammetric determination of quercetin at a multi-walled carbon nanotubes paste electrode, Microchem. J., 85 (2007) 244–249.
  • [9] Chafer A., Pascual M.C., Salvador A., Berna A., Supercritical fluid extraction and HPLC determination of relevant polyphenolic compounds in grape skin, J. Sep. Sci., 28 (2005) 2050–2056.
  • [10] Wu H., Chen M., Fan Y., Elsebaei F., Zhu Y., Determination of rutin and quercetin in Chinese herbal medicine by ionic liquid-based pressurized liquid extraction-liquid chromatography- chemiluminescence detection, Talanta, 88 (2012) 222–229.
  • [11] Ranjbari E., Biparva P., Hadjmohammadi M.R., Utilization of inverted dispersive liquid-liquid microextraction followed by HPLC-UV as a sensitive and efficient method for the extraction and determination of quercetin in honey and biological samples, Talanta, 89 (2012) 117–123.
  • [12] Ulusoy H.İ., Applications of magnetic nanoparticles for the selective extraction of trace species from a complex matrix, 1st ed., New York: Nova Scientific Publishers, (2017).
  • [13] Ulusoy S., Yilmaz E., Erbas Z., Ulusoy H.I., Soylak M., Trace analysis of quercetin in tea samples by HPLC-DAD system by means of a new nanocomposite including magnetic core-shell, Sep. Sci. Technol., (2019).
  • [14] Şenol Z.M., Şimşek S., Ulusoy H.İ., Mahmood A., Kaya S., Insight from adsorption properties of Xylidyl Blue embedded hydrogel for effective removal of uranyl: Experimental and theoretical approaches, Polym. Test., (2020).
  • [15] Memon Z.M., Yilmaz E., Soylak M., Multivariate statistical design optimization for ultrasonic-assisted restricted access supramolecular solvent-based liquid phase microextraction of quercetin in food samples, J. Iran. Chem. Soc., 14 (2017) 2521–2528.
  • [16] Karaca E., Ulusoy S., Morgül U., Ulusoy H.İ., Development of Analytical Method for Sensitive Determination of Streptozotocin based on Solid Phase Extraction, Cumhur. Sci. J., 41 (2020) 826–831.
  • [17] Ulusoy H.I., Şimşek S., Removal of uranyl ions in aquatic mediums by using a new material: Gallocyanine grafted hydrogel, J. Hazard. Mater., 255 (2013) 397-405.
  • [18] Şimşek S., Şenol Z.M., Ulusoy H.İ., Synthesis and characterization of a composite polymeric material including chelating agent for adsorption of uranyl ions, J. Hazard. Mater., 338 (2017) 437–446.
  • [19] Ulusoy H.T., Şimşek S., Removal of uranyl ions in aquatic mediums by using a new material: Gallocyanine grafted hydrogel, J. Hazard. Mater. 254–255 (2013) 397-405.
  • [20] Soylak M., Ozdemir B., Yilmaz E., An environmentally friendly and novel amine-based liquid phase microextraction of quercetin in food samples prior to its determination by UV–vis spectrophotometry, Spectrochim. Acta - Part A Mol. Biomol. Spectrosc., 243 (2020) 118806.
There are 20 citations in total.

Details

Primary Language English
Journal Section Natural Sciences
Authors

Songül Ulusoy 0000-0003-3640-5416

Publication Date September 24, 2021
Submission Date May 15, 2021
Acceptance Date September 7, 2021
Published in Issue Year 2021Volume: 42 Issue: 3

Cite

APA Ulusoy, S. (2021). Synthesis of new solid phase sorbent for sensitive spectrophotometric determination of Quercetin. Cumhuriyet Science Journal, 42(3), 629-637. https://doi.org/10.17776/csj.937421
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