Research Article
Year 2020,
Volume: 41 Issue: 3, 665 - 670, 30.09.2020
Abstract
References
- Inal T., Besin hijyeni, hayvansal gıdaların sağlık kontrolu, Final Ofset, (1992) 55-57.
- Jayalakshmi K., Paramasivam M., Sasikala M., Tamilam T. V., Sumiho A., J. Entomol. Zool. Stud., 5 (2017) 1446-1451.
- Mitchel J., Griffiths M. W., Mceven W. B., Mcnab A. J., Yee A., Antimicrobial drug residues in milk and meat; causes, concerns, prevalence, regulations, tests and test performance, J Food Protect 61(6) (1988) 742-756.
- EC (1990) Council Directive 90/167/EEC of 26 March 1990 laying down the conditions governing the preparation, placing on the market and use of medicated feeding stuffs in the Community, Council Directive 90/167/EEC (1990). Offic J Eur Comm L92:42–48
- Berrada H., Molto J.C., Manes J., Font G., Determination of Aminoglycoside and Macrolide Antibiotics in Meat by Pressurized Liquid Extraction and LC-ESI-MS., J Sep Sci., 33 (2010) 522–529.
- Percin Ozkorucuklu S., Uka B., Yildirim Bastemur G., Voltammetric Analysis of Cephalexin and Cefazolin in Pharmaceutical Formulations and Biological Samples., JOTSCA, 6(2) (2019) 217-224.
- Young-Song J., Jung Hu S., Joo H., Hwang J. B., Kim M. O., Shin J. K., Cho D., Determination of Penicillin Residues in Livestock and Marine Products by LC/MS/MS, WASET, 81 (2011) 809-811.
- Granelli K., Brazzell C., Rapid multi-residue screening of antibiotics in muscle and kidney by liquid chromatography-electrospray ionization–tandem mass spectrometry, J.ACA., 585 (2007) 289-295.
- Furusawa N., Simplified liquid-chromatographic determination of residues of tetracycline antibiotics in eggs, Chromatographia, 53 (2001) 47-50.
- Schneider M. J., Braden S. E., Herrera I. R., Donoghue D. J., Simultaneous determination of fluoroquinolones and tetracyclines in chicken muscle using HPLC with fluorescence detection, J Chromatography B, 846 (2007) 8-13.
- Lu H., Jiang Y., Li H., Chen F., Wong M., Simultaneous determination of oxytetra-cycline, doxycycline, tetracycline and chlortetracycline in tetracycline antibiotics by high-performance liquid chromatography with fluorescence detection, Chromatographia, 60(5-6), 259-264.
- Cháfer-Pericás C., Maquieira A., Puchades R., Fast screening methods to detect antibiotic residues in food samples, TrAC, 29 (9) (2010) 1038-1049.
- Yuvalı D., Narin İ., Simultaneous determination of sulfachloropyridazine and trimethoprim in veterinary formulations by hplc, Cumhuriyet Sci. J., 41(1) (2020) 239-244.
- Bousova K., Senyuva H., Mitterdorf K., Quantitative multi-residue method for determination antibiotics in chicken meat using turbulent flow chromatography coupled to liquid-chromatography-tandem mass spectrometry, J. Chrom. A, 1274 (2013) 19- 27.
- Tong J., Rao Q., Zhu Z., Jiang Z., Ding S., Simultaneous determination of five tetracycline and macrolide antibiotics in feeds using HPCE, J. Sep. Sci., 32 (23-24) (2009) 4254–4260.
- Aszalos A., Fast determination of tetracycline antibiotics in different fast determination of tetracycline antibiotics in different media by High-Performance Liquid Chromatography. Chromatographia, 20 (1985) 313-322.
- Shalaby A. R., Salama N. A., Abouraya S. H., Mehaya F. M., Incidence of tetracycline residues in chicken meat and liver retailed to consumers, Food Chem., 124 (2011) 1660-1666.
- Zief M., Solid Phase Extraction for Sample Preparation, Phillipsburg: JT Baker (2005).
- World Health Organization, 70th report of the Joint FAO/ WHO expert comittee on food additives, Geneva, 21-29 October (2008).
- Magon T., Silveira R., Galuch M. B., Fagan E. P., Feitoza F. D., Palombini S. V., Santos O. O., Visenteiner J. V., Simultaneous determination of four antibiotics in raw milk by UPLC-MS/MS using protein precipitation as sample preparation: Development, validation, and application in real samples, J. Braz. Chem. Soc., 29 (2018) 2441-2448.
- Cetinkaya F., Yibar A., Soyutemiz G. E., Okutan B., Ozcan A., Karaca M. Y., Determination of tetracycline residues in chicken meat by liquid chromatography-tandem mass spectrometry, Food Addit. Contann. Part B Surveill, 5 (2012) 9-45.
- Kowalski P., Koniecznna L., Determination of penicillin antibiotics in poultry muscle by capillary electrophoresis, Bull Vet Inst Pulawy, 51 (2007) 595-598.
- Jammoul A., Darra N., Evaluation of antibiotic residues in chicken meat samples in Lebanon antibiotics, Basel , 8 (2019) 69.
Evaluation of tetracycline, oxytetracycline and penicillin G residues in chicken meat samples by high performance liquid chromatography with pda detection
Abstract
Penicillin G, tetracycline and oxytetracycline are broad-spectrum antibiotics with considerably low side effects which are used in most of the poultries. Due to complex matrix effects, it is considerably difficult to isolate these compounds from other molecules (such as proteins and lipids) in order to analyze. In this study, a high performance liquid chromatography (HPLC) coupled with photodiode array (PDA) detector system was introduced for the determination of tetracycline, oxytetracycline and penicillin G residues in nine chicken breast samples. For the separation of tetracycline and oxytetracycline out of samples prior to the analysis, trichloroacetic acid (TCA) and McIlvaine buffer solutions were used while formic acid and phosphate buffer solutions were utilized for penicillin G using a solid phase extraction system. The peaks at the chromatograms were enlightened and recovery percentages were calculated using spiked samples (96.57% for penicillin G; 99.00% for oxytetracycline; 95.92% for tetracycline). LOD and LOQ values were calculated, respectively as 1.55 gL-1 and 5.20 gL-1 for tetracycline; 1.32 gL-1 and 4.39 gL-1 for oxytetracycline; 1.07 gL-1 and 3.60 gL-1 for penicillin G. With the proposed method, the determination of three antibiotic residues was performed in less than 15 minutes and applied successfully to real samples.
References
- Inal T., Besin hijyeni, hayvansal gıdaların sağlık kontrolu, Final Ofset, (1992) 55-57.
- Jayalakshmi K., Paramasivam M., Sasikala M., Tamilam T. V., Sumiho A., J. Entomol. Zool. Stud., 5 (2017) 1446-1451.
- Mitchel J., Griffiths M. W., Mceven W. B., Mcnab A. J., Yee A., Antimicrobial drug residues in milk and meat; causes, concerns, prevalence, regulations, tests and test performance, J Food Protect 61(6) (1988) 742-756.
- EC (1990) Council Directive 90/167/EEC of 26 March 1990 laying down the conditions governing the preparation, placing on the market and use of medicated feeding stuffs in the Community, Council Directive 90/167/EEC (1990). Offic J Eur Comm L92:42–48
- Berrada H., Molto J.C., Manes J., Font G., Determination of Aminoglycoside and Macrolide Antibiotics in Meat by Pressurized Liquid Extraction and LC-ESI-MS., J Sep Sci., 33 (2010) 522–529.
- Percin Ozkorucuklu S., Uka B., Yildirim Bastemur G., Voltammetric Analysis of Cephalexin and Cefazolin in Pharmaceutical Formulations and Biological Samples., JOTSCA, 6(2) (2019) 217-224.
- Young-Song J., Jung Hu S., Joo H., Hwang J. B., Kim M. O., Shin J. K., Cho D., Determination of Penicillin Residues in Livestock and Marine Products by LC/MS/MS, WASET, 81 (2011) 809-811.
- Granelli K., Brazzell C., Rapid multi-residue screening of antibiotics in muscle and kidney by liquid chromatography-electrospray ionization–tandem mass spectrometry, J.ACA., 585 (2007) 289-295.
- Furusawa N., Simplified liquid-chromatographic determination of residues of tetracycline antibiotics in eggs, Chromatographia, 53 (2001) 47-50.
- Schneider M. J., Braden S. E., Herrera I. R., Donoghue D. J., Simultaneous determination of fluoroquinolones and tetracyclines in chicken muscle using HPLC with fluorescence detection, J Chromatography B, 846 (2007) 8-13.
- Lu H., Jiang Y., Li H., Chen F., Wong M., Simultaneous determination of oxytetra-cycline, doxycycline, tetracycline and chlortetracycline in tetracycline antibiotics by high-performance liquid chromatography with fluorescence detection, Chromatographia, 60(5-6), 259-264.
- Cháfer-Pericás C., Maquieira A., Puchades R., Fast screening methods to detect antibiotic residues in food samples, TrAC, 29 (9) (2010) 1038-1049.
- Yuvalı D., Narin İ., Simultaneous determination of sulfachloropyridazine and trimethoprim in veterinary formulations by hplc, Cumhuriyet Sci. J., 41(1) (2020) 239-244.
- Bousova K., Senyuva H., Mitterdorf K., Quantitative multi-residue method for determination antibiotics in chicken meat using turbulent flow chromatography coupled to liquid-chromatography-tandem mass spectrometry, J. Chrom. A, 1274 (2013) 19- 27.
- Tong J., Rao Q., Zhu Z., Jiang Z., Ding S., Simultaneous determination of five tetracycline and macrolide antibiotics in feeds using HPCE, J. Sep. Sci., 32 (23-24) (2009) 4254–4260.
- Aszalos A., Fast determination of tetracycline antibiotics in different fast determination of tetracycline antibiotics in different media by High-Performance Liquid Chromatography. Chromatographia, 20 (1985) 313-322.
- Shalaby A. R., Salama N. A., Abouraya S. H., Mehaya F. M., Incidence of tetracycline residues in chicken meat and liver retailed to consumers, Food Chem., 124 (2011) 1660-1666.
- Zief M., Solid Phase Extraction for Sample Preparation, Phillipsburg: JT Baker (2005).
- World Health Organization, 70th report of the Joint FAO/ WHO expert comittee on food additives, Geneva, 21-29 October (2008).
- Magon T., Silveira R., Galuch M. B., Fagan E. P., Feitoza F. D., Palombini S. V., Santos O. O., Visenteiner J. V., Simultaneous determination of four antibiotics in raw milk by UPLC-MS/MS using protein precipitation as sample preparation: Development, validation, and application in real samples, J. Braz. Chem. Soc., 29 (2018) 2441-2448.
- Cetinkaya F., Yibar A., Soyutemiz G. E., Okutan B., Ozcan A., Karaca M. Y., Determination of tetracycline residues in chicken meat by liquid chromatography-tandem mass spectrometry, Food Addit. Contann. Part B Surveill, 5 (2012) 9-45.
- Kowalski P., Koniecznna L., Determination of penicillin antibiotics in poultry muscle by capillary electrophoresis, Bull Vet Inst Pulawy, 51 (2007) 595-598.
- Jammoul A., Darra N., Evaluation of antibiotic residues in chicken meat samples in Lebanon antibiotics, Basel , 8 (2019) 69.
There are 23 citations in total.
Details
| Primary Language | English |
|---|---|
| Journal Section | Natural Sciences |
| Authors | |
| Publication Date | September 30, 2020 |
| Submission Date | April 20, 2020 |
| Acceptance Date | August 4, 2020 |
| Published in Issue | Year 2020Volume: 41 Issue: 3 |