Research Article
BibTex RIS Cite

Poli (p-Aminobenzen Sülfonik Asit) Modifiye Sensöründe Askorbik Asit Varlığında Epinefrinin Elektrokimyasal Tayini

Year 2018, Volume: 39 Issue: 4, 1025 - 1035, 24.12.2018

Şevket Zişan Bilge Yağcı Ebru Kuyumcu Savan , Gamze Erdoğdu

https://doi.org/10.17776/csj.426874

Abstract

Poli (p-aminobenzen
sülfonik asit, ABSA) modifiye sensör ile askorbik asit varlığında epinefrinin
(EP) hızlı, güvenilir ve duyarlı bir şekilde seçici ve eş zamanlı voltametrik
tayini gerçekleştirildi. Camsı karbon elektrot, ABSA ile 0.1 M KCl çözeltisi
içerisinde çevrimli voltametri tekniğiyle başarılı bir şekilde modifiye edildi.
Polimerik ince film ile modifiye edilen sensör, EP ve askorbik asitin (AA)
yükseltgenmesine karşı mükemmel elektro-katalitik etki göstermiştir. Sonuçlar,
her iki türün oksidasyon potansiyeli ve oksidasyon pik akım yanıtlarının önemli
derecede iyileştiğini göstermiştir. Modifiye sensör, optimum koşullar altında
EP tayinine karşı 5.0–53.2 µM derişim aralığında 50 nM tayin sınırı ile
mükemmel cevap göstermiştir. Farmasötik preparatta ve kan serumunda
gerçekleştirilen gerçek numune analizlerinde geri kazanım değerleri % 98.4 -
77.3 di. Elde edilen sonuçlar, modifiye sensörün AA varlığında EP’in
saptanmasında uygulanabileceğini göstermiştir. Önerilen sensörün, yüksek
seçicilik, tekrarlanabilirlik, tekrarüretilebilirlik ve uzun-süreli kararlılık
özelliklerinden ve farmasötik ve biyolojik örneklerde elde edilen yüksek geri
kazanım değerlerinden dolayı rutin analizlerde uygulanabilecek olması umut
vericidir.

Keywords

Epinefrin p-aminobenzen sülfonik asit sensör voltametri

References

  • [1]. Tavana, T., Khalilzadeh, M.A., Karimi-Maleh, H., Ensafi, A.A., Beitollahi, H. and Zareyee, D., Sensitive voltammetric determination of epinephrine in the presence of acetaminophen at a novel ionic liquid modified carbon nanotubes paste electrode, J. Mol. Liq., 168 (2012) 69–74.
  • [2]. Jackson, L., Williams, F.L.R., Burchell, A., Coughtrie M.W.H. and Hume, R., Plasma catecholamines and the counterregulatory responses to hypoglycemia in infants: A critical role for epinephrine and cortisol, J. Clin. Endocrinol. Metab., 89-12 (2004) 6251–6256.
  • [3]. Bergquist, J., Ciubisz, A., Kaczor, A. and Silberring, J. Catecholamines and methods for their identification and quantitation in biological tissues and fluids. J. Neurosci. Meth. 113 (2002) 1–13.
  • [4]. Martinez-Quintana, E. et al. Acute myocardial infarction secondary to catecholamine release owing to cocaine abuse and pheochromocytoma crisis. Int. J. Endocrinol. Metab., 11 (2013) 48–51.
  • [5]. Beitollahi, H., Ardakani, M.M., Ganjipour, B. and Naeimi, H. Novel 2,2′-[1,2-ethanediylbis(nitriloethylidyne)]-bis-hydroquinone double-wall carbon nanotube paste electrode for simultaneous determination of epinephrine, uric acid and folic acid. Biosens. Bioelectron., 24 (2008) 362–368.
  • [6]. Jin, G.-P., Lin, X.-Q. and Gong, J. Novel choline and acetylcholine modified glassy carbon electrodes for simultaneous determination of dopamine, serotonin and ascorbic acid. J. Electroanal. Chem., 569 (2004) 135–142.
  • [7]. Mazloum-Ardakani, M., Talebi, A., Naeimib, H. and Sheikh-Mohseni, M.A. Electrocatalysis of epinephrine by TiO2 nanoparticles and 2,20-[1,7- hepthandiylbis(nitriloethylidyne)]-bis-hydroquinone modified carbon paste electrode. Anal. Methods, 3 (2011) 2328–2333.
  • [8]. Mazloum-Ardakani, M. et al. Simultaneous determination of epinephrine and acetaminophen concentrations using a novel carbon paste electrode prepared with 2,2′-[1,2 butanediylbis(nitriloethylidyne)]-bis-hydroquinone and TiO2nanoparticles. Colloids Surfaces B Biointerfaces 76 (2010)82–87.
  • [9]. Wong, D.L., Tai, T.C., Wong-Faull, D.C., Claycomb, R. and Kvetňanský, R. Adrenergic responses to stress: Transcriptional and post-transcriptional changes. Ann. N. Y. Acad. Sci., 1148 (2008) 249–256.
  • [10]. Carbone, M., Nesticò, A., Bellucci, N., Micheli, L. and Palleschi, G. Enhanced performances of sensors based on screen printed electrodes modified with nanosized NiO particles. Electrochim. Acta, 246 (2017) 580–587.
  • [11]. Zhang, W., He, L., Gu, Y., Liu, X. and Jiang, S. Effect of ionic liquids as mobile phase additives on retention of catecholamines in reversed-phase high-performance liquid chromatography. Anal. Lett., 36 (2003) 827–838.
  • [12]. Babaei, A., Sohrabi, M. and Afrasiabi, M. A Sensitive Simultaneous Determination of Epinephrine and Piroxicam Using a Glassy Carbon Electrode Modified with a Nickel Hydroxide Nanoparticles/Multiwalled Carbon Nanotubes Composite. Electroanalysis, 24 (2012) 2387–2394.
  • [13]. Niu, L.M., Luo, H.Q. and Li, N.B. Electrochemical behavior of epinephrine at a penicillamine self-assembled gold electrode, and its analytical application. Microchim. Acta 150 (2005) 87–93.
  • [14]. Wang, L. et al. Electrochemical behavior and determination of epinephrine at a penicillamine self-assembled gold electrode. Int. J. Electrochem. Sci., 1 (2006) 238–249.
  • [15]. Niu, L.M., Luo, H.Q. and Li, N.B. Electrochemical behavior of uric acid at a meso-2,3-dimercaptosuccinic acid self-assembled gold electrode. Instrum. Sci. Technol., 35 (2007) 59–73.
  • [16]. Fang, C., Tang, X. and Zhou, X. Preparation of Poly(malachite green) Modified Electrode and the Determination of Dopamine and Ascorbic Acid. Anal. Sci., 15 (1999) 41–46.
  • [17]. Kumar, S.S., Mathiyarasu, J., Phani, K.L., Jain, Y.K. and Yegnaraman, V. Determination of uric acid in the presence of ascorbic acid using poly(3,4-ethylenedioxythiophene)-modified electrodes. Electroanalysis, 17 (2005) 2281–2286.
  • [18]. Zhao, Y., Bai, J., Wang, L., Huang, P. and Wang, H. Simultaneous Electrochemical Determination of Uric Acid and Ascorbic Acid Using L -Cysteine Self-Assembled Gold Electrode. Int. J. Electrochem. Sci., 1 (2006) 363–371.
  • [19]. Yang, Z., Hu, G., Chen, X., Zhao, J. and Zhao, G. The nano-Au self-assembled glassy carbon electrode for selective determination of epinephrine in the presence of ascorbic acid. Colloids Surfaces B Biointerfaces, 54 (2007) 230–235.
  • [20]. Wang, H.-S., Li, T.-H., Jia, W.-L. and Xu, H.-Y. Highly selective and sensitive determination of dopamine using a Nafion/carbon nanotubes coated poly(3-methylthiophene) modified electrode. Biosens. Bioelectron., 22 (2006) 664–669.
  • [21]. Savan, E.K. and Erdoğdu, G. Determination of 3,4-dihydroxyphenylacetic acid in the presence of ascorbic acid and uric acid at poly(p-aminobenzene sulfonic acid) conducting polymer electrode. Polym. Bull., 74-10 (2017) 4349-4360.
  • [22]. Erdoğdu, G. and Mutlu, M.M. Selective Detection of Dopamine in the Presence of Ascorbic Acid at Poly (m-Aminobenzene Sulfonic Acid). Am. J. Anal. Chem., 02 (2011) 582–588.
  • [23]. Jin, G., Zhang, Y. and Cheng, W. Poly(p-aminobenzene sulfonic acid)-modified glassy carbon electrode for simultaneous detection of dopamine and ascorbic acid. Sensors Actuators B Chem., 107 (2005) 528–534.
  • [24]. Ren, W., Luo, H.Q. and Li, N.B. Electrochemical behavior of epinephrine at a glassy carbon electrode modified by electrodeposited films of caffeic acid. Sensors, 6 (2006) 80–89.
  • [25]. Wierzbicka, E. and Sulka, G.D. Nanoporous spongelike Au–Ag films for electrochemical epinephrine sensing. J. Electroanal. Chem., 762 (2016) 43–50.
  • [26]. Shahrokhian, S., Ghalkhani, M. and Amini, M.K. Application of carbon-paste electrode modified with iron phthalocyanine for voltammetric determination of epinephrine in the presence of ascorbic acid and uric acid. Sensors Actuators, B Chem., 137 (2009) 669–675.
  • [27]. Bakir C.C., Preparation and characterization of metal nano particles modified carbon nanotube and polymer film electrodes and their analytical applications. Ege Üniversitesi, Fen Bilimleri Enstitüsü, (2010).
  • [28]. Rostami, A. and Taylor, M.S. Polymers for anion recognition and sensing. Macromol. Rap. Commun., 33 (2012) 21-34.
  • [29]. Liu, H., Zhao, G., Wen, L. and Ye, B. Simultaneous voltammetric determination of epinephrine and serotonin at a p-tetra-butyl calix [6] arene-L-Histidine chemically modified electrode. J. Anal. Chem., 61 (2006) 1104–1107.
  • [30]. Gong, J. and Lin, X. A glassy carbon supported bilayer lipid-like membrane of 5,5-ditetradecyl-2-(2-trimethyl-ammonioethyl)-1,3-dioxane bromide for electrochemical sensing of epinephrine. Electrochim. Acta, 49 (2004) 4351–4357.
  • [31]. Ren, W., Luo, H.Q. and Li, N. B. Simultaneous voltammetric measurement of ascorbic acid, epinephrine and uric acid at a glassy carbon electrode modified with caffeic acid. Biosens. Bioelectron., 21 (2006) 1086–1092.
  • [32]. Yogeswaran, U., Thiagarajan, S. and Chen, S.-M. Nanocomposite of functionalized multiwall carbon nanotubes with nafion, nano platinum, and nano gold biosensing film for simultaneous determination of ascorbic acid, epinephrine, and uric acid. Anal. Biochem., 365 (2007) 122–131.
  • [33]. Cheng, W., Jin, G. and Zhang, Y. Electrochemical Characteristics of Poly ( o -Aminobenzoic Acid ) Modified Glassy-Carbon Electrode and Its Electrocatalytic Activity towards Oxidation of Epinephrine . Russ. J. Electrochem., 41 (2005) 940–945.
  • [34]. Taylor, P., He, Y. Bin, Luo, H. Q. and Li, N. B. Electrochemical Behavior of Epinephrine at Two ‐ Component Self ‐ Assembled Monolayer of meso ‐ 2 , 3 ‐ Dimercaptosuccinic Acid and Penicillamine on Gold Electrode. Instr. Sci. Technol., 35 (2007) 163–175.

Electrochemical Detection of Epinephrine in The Presence of Ascorbic Acid at Poly (p-Aminobenzene Sulfonic Acid) Modified Sensor

Year 2018, Volume: 39 Issue: 4, 1025 - 1035, 24.12.2018

Şevket Zişan Bilge Yağcı Ebru Kuyumcu Savan , Gamze Erdoğdu

https://doi.org/10.17776/csj.426874

Abstract

In this study, a rapid, reliable, selective and sensitive simultaneous
voltammetric determination of Epinephrine (EP) in the presence of ascorbic acid
at poly (p-aminobenzene sulphonic
acid, ABSA) modified sensor was aimed. The glassy carbon electrode was
successfully modified with ABSA in 0.1 M KCl solution by the cycling
voltammetry technique. The sensor, modified with a polymeric thin film, showed
excellent electrocatalytic activity against the oxidation of EP and ascorbic
acid (AA). The results showed that the oxidation potential and current
responses of EP and AA improved significantly. The modified sensor showed
excellent response with limit of detection as 50 nM in the determination of EP
at the 5.0 - 53.2 μM concentration range under optimum conditions. In real
sample analyzes performed in pharmaceutical preparation and blood serum,
recovery values were 77.3%-98.4%. The results obtained show that the modified
sensor can be applied to the detection of EP in the presence of AA. The proposed
sensor is promising for routine analysis because of its high selectivity,
reproducibility, reproducibility and long-term stability characteristics and
high recovery values obtained in pharmaceutical and biological samples.

Keywords

Epinephrine p-aminobenzene sulfonic acid sensor voltammetry voltammetry

References

  • [1]. Tavana, T., Khalilzadeh, M.A., Karimi-Maleh, H., Ensafi, A.A., Beitollahi, H. and Zareyee, D., Sensitive voltammetric determination of epinephrine in the presence of acetaminophen at a novel ionic liquid modified carbon nanotubes paste electrode, J. Mol. Liq., 168 (2012) 69–74.
  • [2]. Jackson, L., Williams, F.L.R., Burchell, A., Coughtrie M.W.H. and Hume, R., Plasma catecholamines and the counterregulatory responses to hypoglycemia in infants: A critical role for epinephrine and cortisol, J. Clin. Endocrinol. Metab., 89-12 (2004) 6251–6256.
  • [3]. Bergquist, J., Ciubisz, A., Kaczor, A. and Silberring, J. Catecholamines and methods for their identification and quantitation in biological tissues and fluids. J. Neurosci. Meth. 113 (2002) 1–13.
  • [4]. Martinez-Quintana, E. et al. Acute myocardial infarction secondary to catecholamine release owing to cocaine abuse and pheochromocytoma crisis. Int. J. Endocrinol. Metab., 11 (2013) 48–51.
  • [5]. Beitollahi, H., Ardakani, M.M., Ganjipour, B. and Naeimi, H. Novel 2,2′-[1,2-ethanediylbis(nitriloethylidyne)]-bis-hydroquinone double-wall carbon nanotube paste electrode for simultaneous determination of epinephrine, uric acid and folic acid. Biosens. Bioelectron., 24 (2008) 362–368.
  • [6]. Jin, G.-P., Lin, X.-Q. and Gong, J. Novel choline and acetylcholine modified glassy carbon electrodes for simultaneous determination of dopamine, serotonin and ascorbic acid. J. Electroanal. Chem., 569 (2004) 135–142.
  • [7]. Mazloum-Ardakani, M., Talebi, A., Naeimib, H. and Sheikh-Mohseni, M.A. Electrocatalysis of epinephrine by TiO2 nanoparticles and 2,20-[1,7- hepthandiylbis(nitriloethylidyne)]-bis-hydroquinone modified carbon paste electrode. Anal. Methods, 3 (2011) 2328–2333.
  • [8]. Mazloum-Ardakani, M. et al. Simultaneous determination of epinephrine and acetaminophen concentrations using a novel carbon paste electrode prepared with 2,2′-[1,2 butanediylbis(nitriloethylidyne)]-bis-hydroquinone and TiO2nanoparticles. Colloids Surfaces B Biointerfaces 76 (2010)82–87.
  • [9]. Wong, D.L., Tai, T.C., Wong-Faull, D.C., Claycomb, R. and Kvetňanský, R. Adrenergic responses to stress: Transcriptional and post-transcriptional changes. Ann. N. Y. Acad. Sci., 1148 (2008) 249–256.
  • [10]. Carbone, M., Nesticò, A., Bellucci, N., Micheli, L. and Palleschi, G. Enhanced performances of sensors based on screen printed electrodes modified with nanosized NiO particles. Electrochim. Acta, 246 (2017) 580–587.
  • [11]. Zhang, W., He, L., Gu, Y., Liu, X. and Jiang, S. Effect of ionic liquids as mobile phase additives on retention of catecholamines in reversed-phase high-performance liquid chromatography. Anal. Lett., 36 (2003) 827–838.
  • [12]. Babaei, A., Sohrabi, M. and Afrasiabi, M. A Sensitive Simultaneous Determination of Epinephrine and Piroxicam Using a Glassy Carbon Electrode Modified with a Nickel Hydroxide Nanoparticles/Multiwalled Carbon Nanotubes Composite. Electroanalysis, 24 (2012) 2387–2394.
  • [13]. Niu, L.M., Luo, H.Q. and Li, N.B. Electrochemical behavior of epinephrine at a penicillamine self-assembled gold electrode, and its analytical application. Microchim. Acta 150 (2005) 87–93.
  • [14]. Wang, L. et al. Electrochemical behavior and determination of epinephrine at a penicillamine self-assembled gold electrode. Int. J. Electrochem. Sci., 1 (2006) 238–249.
  • [15]. Niu, L.M., Luo, H.Q. and Li, N.B. Electrochemical behavior of uric acid at a meso-2,3-dimercaptosuccinic acid self-assembled gold electrode. Instrum. Sci. Technol., 35 (2007) 59–73.
  • [16]. Fang, C., Tang, X. and Zhou, X. Preparation of Poly(malachite green) Modified Electrode and the Determination of Dopamine and Ascorbic Acid. Anal. Sci., 15 (1999) 41–46.
  • [17]. Kumar, S.S., Mathiyarasu, J., Phani, K.L., Jain, Y.K. and Yegnaraman, V. Determination of uric acid in the presence of ascorbic acid using poly(3,4-ethylenedioxythiophene)-modified electrodes. Electroanalysis, 17 (2005) 2281–2286.
  • [18]. Zhao, Y., Bai, J., Wang, L., Huang, P. and Wang, H. Simultaneous Electrochemical Determination of Uric Acid and Ascorbic Acid Using L -Cysteine Self-Assembled Gold Electrode. Int. J. Electrochem. Sci., 1 (2006) 363–371.
  • [19]. Yang, Z., Hu, G., Chen, X., Zhao, J. and Zhao, G. The nano-Au self-assembled glassy carbon electrode for selective determination of epinephrine in the presence of ascorbic acid. Colloids Surfaces B Biointerfaces, 54 (2007) 230–235.
  • [20]. Wang, H.-S., Li, T.-H., Jia, W.-L. and Xu, H.-Y. Highly selective and sensitive determination of dopamine using a Nafion/carbon nanotubes coated poly(3-methylthiophene) modified electrode. Biosens. Bioelectron., 22 (2006) 664–669.
  • [21]. Savan, E.K. and Erdoğdu, G. Determination of 3,4-dihydroxyphenylacetic acid in the presence of ascorbic acid and uric acid at poly(p-aminobenzene sulfonic acid) conducting polymer electrode. Polym. Bull., 74-10 (2017) 4349-4360.
  • [22]. Erdoğdu, G. and Mutlu, M.M. Selective Detection of Dopamine in the Presence of Ascorbic Acid at Poly (m-Aminobenzene Sulfonic Acid). Am. J. Anal. Chem., 02 (2011) 582–588.
  • [23]. Jin, G., Zhang, Y. and Cheng, W. Poly(p-aminobenzene sulfonic acid)-modified glassy carbon electrode for simultaneous detection of dopamine and ascorbic acid. Sensors Actuators B Chem., 107 (2005) 528–534.
  • [24]. Ren, W., Luo, H.Q. and Li, N.B. Electrochemical behavior of epinephrine at a glassy carbon electrode modified by electrodeposited films of caffeic acid. Sensors, 6 (2006) 80–89.
  • [25]. Wierzbicka, E. and Sulka, G.D. Nanoporous spongelike Au–Ag films for electrochemical epinephrine sensing. J. Electroanal. Chem., 762 (2016) 43–50.
  • [26]. Shahrokhian, S., Ghalkhani, M. and Amini, M.K. Application of carbon-paste electrode modified with iron phthalocyanine for voltammetric determination of epinephrine in the presence of ascorbic acid and uric acid. Sensors Actuators, B Chem., 137 (2009) 669–675.
  • [27]. Bakir C.C., Preparation and characterization of metal nano particles modified carbon nanotube and polymer film electrodes and their analytical applications. Ege Üniversitesi, Fen Bilimleri Enstitüsü, (2010).
  • [28]. Rostami, A. and Taylor, M.S. Polymers for anion recognition and sensing. Macromol. Rap. Commun., 33 (2012) 21-34.
  • [29]. Liu, H., Zhao, G., Wen, L. and Ye, B. Simultaneous voltammetric determination of epinephrine and serotonin at a p-tetra-butyl calix [6] arene-L-Histidine chemically modified electrode. J. Anal. Chem., 61 (2006) 1104–1107.
  • [30]. Gong, J. and Lin, X. A glassy carbon supported bilayer lipid-like membrane of 5,5-ditetradecyl-2-(2-trimethyl-ammonioethyl)-1,3-dioxane bromide for electrochemical sensing of epinephrine. Electrochim. Acta, 49 (2004) 4351–4357.
  • [31]. Ren, W., Luo, H.Q. and Li, N. B. Simultaneous voltammetric measurement of ascorbic acid, epinephrine and uric acid at a glassy carbon electrode modified with caffeic acid. Biosens. Bioelectron., 21 (2006) 1086–1092.
  • [32]. Yogeswaran, U., Thiagarajan, S. and Chen, S.-M. Nanocomposite of functionalized multiwall carbon nanotubes with nafion, nano platinum, and nano gold biosensing film for simultaneous determination of ascorbic acid, epinephrine, and uric acid. Anal. Biochem., 365 (2007) 122–131.
  • [33]. Cheng, W., Jin, G. and Zhang, Y. Electrochemical Characteristics of Poly ( o -Aminobenzoic Acid ) Modified Glassy-Carbon Electrode and Its Electrocatalytic Activity towards Oxidation of Epinephrine . Russ. J. Electrochem., 41 (2005) 940–945.
  • [34]. Taylor, P., He, Y. Bin, Luo, H. Q. and Li, N. B. Electrochemical Behavior of Epinephrine at Two ‐ Component Self ‐ Assembled Monolayer of meso ‐ 2 , 3 ‐ Dimercaptosuccinic Acid and Penicillamine on Gold Electrode. Instr. Sci. Technol., 35 (2007) 163–175.
There are 34 citations in total.

Details

Primary Language English
Journal Section Natural Sciences
Authors

Şevket Zişan Bilge Yağcı 0000-0002-6064-3177

Ebru Kuyumcu Savan 0000-0002-8851-0907

Gamze Erdoğdu 0000-0002-8114-6946

Publication Date December 24, 2018
Submission Date May 25, 2018
Acceptance Date December 6, 2018
Published in Issue Year 2018Volume: 39 Issue: 4

Cite

APA Yağcı, Ş. Z. B., Kuyumcu Savan, E., & Erdoğdu, G. (2018). Electrochemical Detection of Epinephrine in The Presence of Ascorbic Acid at Poly (p-Aminobenzene Sulfonic Acid) Modified Sensor. Cumhuriyet Science Journal, 39(4), 1025-1035. https://doi.org/10.17776/csj.426874