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Evaluation of dosimetric impact of Flattening Filter-Free (FFF) Photon Beams in 3D conformal radiotherapy

Year 2018, Volume: 39 Issue: 1, 196 - 200, 16.03.2018

Cherif Kourtelı Fatima Benrachı

https://doi.org/10.17776/csj.359904

Abstract

Flattening Filter Free (FFF) photon beams have been
frequently used in radiotherapy clinical practice. This study aimed to analyze
the dosimetric quality of the FFF beams, as compared to the standard flattened
beams (FB) for plans of treatment of three patients involving three cancer
sites using the 6 and 10 MV photon energies and the 3D conformal radiotherapy
technique (3D-CRT). The doses to the planning target volumes (PTVs) and organs
at risk (OARs) were compared. The dose-volume histogram curves analysis show
that no significant differences between FFF and FB plans were found in the
coverage and mean dose for the PTV, the OAR revealed slight differences. So the
FFF
photon beam achieved comparable dosimetric quality as the standard flat beam.

Keywords

Flattening Filter Free (FFF) 3D conformal radiotherapy (3D-CRT) Treatment planning Dosimetric evaluation

References

  • [1]. Podgorsak E.B, Radiation Oncology Physics: A Handbook for Teachers and Students. International Atomic Energy Agency, 2005.
  • [2]. Fogliata A & al, Definition of parameters for quality assurance of flattening filter free (FFF) photon beams in radiation therapy, J. Med. Phys, 39 (2012) 6455- 64.
  • [3]. Rout BK, Muralidhar KR, Ali M, Shekar MC and Kumar A, Dosimetric study of RapidArc plans with flattened beam (FB) and flattening filter-free (FFF) beam for localized prostate cancer based on physical indices. Int. J. Cancer Ther. Oncol., 2 (2014) 2046.
  • [4]. M. Kretschmer & al, The impact of flattening-filter-free beam technology on 3D conformal RT, J. Radiat Oncol., 8 (2013) 133.
  • [5]. Stathakis S and al, Treatment planning and delivery of IMRT using 6 and 18 MV photon beams without flattening filter. Applied Radiation and Isotopes, 67 (2009) 1629-37
  • [6]. Mingzan Z and al, Volumetric modulation arc radiotherapy with flattening filter-free beams compared with conventional beams for nasopharyngeal carcinoma: a feasibility study, Chin. J. Cancer, 32 (2013) 397-402.
  • [7]. Stevens S.W, Rosser K.E, and Bedford J.L, A 4 MV flattening filter free beam: Commissioning and application to conformal therapy and volumetric modulated arc therapy, J. Phys Med Biol., 56 (2011) 3809-24.
  • [8]. Scorsetti M and al, Feasibility and early clinical assessment of flattening filter free (FFF) based stereotactic body radiotherapy (SBRT) treatments, J. Radiat Oncol., 6 (2011) 113.
  • [9]. Vassiliev O.N and al, Stereotactic radiotherapy for lung cancer using a flattening filter free Clinac, J. Appl Clin Med Phys., 10 ( 2009) 14–21.
  • [10]. Georg D, Knöös T, McClean B, Current status and future perspective of flattening filter free photon beams, J. Med Phys., 38 (2011) 1280-93.
  • [11]. Wang Y, Khan M.K, Ting J.Y, Easterling S.B, Surface dose investigation of the flattening filter-free photon beams, J. Radiat Oncol Biol Phys., 83 (2011) 281-285.

Düzleştirici Filtresiz Foton Kirişlerin (FFF) 3D Konformal Radyoterapide Dozimetrik Etkilerinin Değerlendirilmesi

Year 2018, Volume: 39 Issue: 1, 196 - 200, 16.03.2018

Cherif Kourtelı Fatima Benrachı

https://doi.org/10.17776/csj.359904

Abstract

Düzleştirici Filtre Serbest (FFF) foton
ışınları, radyoterapi klinik pratiğinde sıklıkla kullanılmaktadır. Bu
çalışmada, 6 ve 10 MV foton enerjileri ve 3D konformal radyoterapi tekniği
(3D-CRT) kullanılarak üç kanser bölgesi içeren üç hastanın tedavi planları için
standart düzleştirilmiş kirişlere (FB) kıyasla FFF ışınlarının dozimetrik
kalitesini analiz etmeyi amaçladık. Planlanan hedef hacim dozları (PTV'ler) ve
risk altındaki organlar (OAR'ler) karşılaştırıldı. Doz-hacim histogram eğrileri
analizi, FFF ve FB planları arasında PTV için ortalama doz ve ortalama doz
arasında anlamlı bir fark bulunmadığını, OAR'ın hafif farklılıklar olduğunu
göstermektedir. Böylece FFF foton ışını, standart düz kiriş olarak
karşılaştırılabilir dozimetrik kaliteye ulaşmıştır.

Keywords

Düzleştirici Filtresiz (FFF) 3D konformal radyoterapi (3D-CRT) Tedavi planlaması Dozimetrik değerlendirme

References

  • [1]. Podgorsak E.B, Radiation Oncology Physics: A Handbook for Teachers and Students. International Atomic Energy Agency, 2005.
  • [2]. Fogliata A & al, Definition of parameters for quality assurance of flattening filter free (FFF) photon beams in radiation therapy, J. Med. Phys, 39 (2012) 6455- 64.
  • [3]. Rout BK, Muralidhar KR, Ali M, Shekar MC and Kumar A, Dosimetric study of RapidArc plans with flattened beam (FB) and flattening filter-free (FFF) beam for localized prostate cancer based on physical indices. Int. J. Cancer Ther. Oncol., 2 (2014) 2046.
  • [4]. M. Kretschmer & al, The impact of flattening-filter-free beam technology on 3D conformal RT, J. Radiat Oncol., 8 (2013) 133.
  • [5]. Stathakis S and al, Treatment planning and delivery of IMRT using 6 and 18 MV photon beams without flattening filter. Applied Radiation and Isotopes, 67 (2009) 1629-37
  • [6]. Mingzan Z and al, Volumetric modulation arc radiotherapy with flattening filter-free beams compared with conventional beams for nasopharyngeal carcinoma: a feasibility study, Chin. J. Cancer, 32 (2013) 397-402.
  • [7]. Stevens S.W, Rosser K.E, and Bedford J.L, A 4 MV flattening filter free beam: Commissioning and application to conformal therapy and volumetric modulated arc therapy, J. Phys Med Biol., 56 (2011) 3809-24.
  • [8]. Scorsetti M and al, Feasibility and early clinical assessment of flattening filter free (FFF) based stereotactic body radiotherapy (SBRT) treatments, J. Radiat Oncol., 6 (2011) 113.
  • [9]. Vassiliev O.N and al, Stereotactic radiotherapy for lung cancer using a flattening filter free Clinac, J. Appl Clin Med Phys., 10 ( 2009) 14–21.
  • [10]. Georg D, Knöös T, McClean B, Current status and future perspective of flattening filter free photon beams, J. Med Phys., 38 (2011) 1280-93.
  • [11]. Wang Y, Khan M.K, Ting J.Y, Easterling S.B, Surface dose investigation of the flattening filter-free photon beams, J. Radiat Oncol Biol Phys., 83 (2011) 281-285.
There are 11 citations in total.

Details

Primary Language English
Journal Section Natural Sciences
Authors

Cherif Kourtelı

Fatima Benrachı

Publication Date March 16, 2018
Submission Date November 30, 2017
Acceptance Date January 31, 2018
Published in Issue Year 2018Volume: 39 Issue: 1

Cite

APA Kourtelı, C., & Benrachı, F. (2018). Evaluation of dosimetric impact of Flattening Filter-Free (FFF) Photon Beams in 3D conformal radiotherapy. Cumhuriyet Science Journal, 39(1), 196-200. https://doi.org/10.17776/csj.359904
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