Research Article
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Year 2021, , 722 - 727, 24.09.2021
https://doi.org/10.17776/csj.677410

Abstract

References

  • [1] Teksöz S., Müftüler FZB., Radioisotopes and Biomedical Applications in Nuclear Medicine, Nucl Med Semin, 5 (2019) 10-14.
  • [2] Andreyev, A., Sitek, A., & Celler, A. (2014). EM reconstruction of dual isotope PET using staggered injections and prompt gamma positron emitters, Medical Physics, 41(2) (2014) 022501.
  • [3] Andreyev, A., Celler, A., Dual-isotope PET using positron gamma emitters, Phys. Med. Biol. 56 (4539) (2011).
  • [4] Figueiras, F. P., et al., Simultaneous dual-tracer PET imaging of the ratbrain and its application in the study of cerebral ischemia, Mol. Imag. Biol., vol. 13(3) (2011) 500–510.
  • [5] Black, N. F. , Mcjames, S. and Kadrmas, D.J., Rapid multi-tracer PET tumor imaging with [18F] FDG and secondary shorter-lived tracers, IEEE Trans. Nucl. Sci., 56(5) (2009) 2750–2758.
  • [6] El Fakhri, G., Sitek, A. and Guerin, B., Simultaneous dual tracer PET using generalized factor analysis of dynamic sequences, Proc. Nucl.Sci. Symp. Conf. Rec., 15 (2006) 2128–2130.
  • [7] Jan, S. et al. , GATE: a simulation toolkit for PET and SPECT, Phys. Med. Biol., 49 (2004) 4543-4561.
  • [8] Brun, R., & Rademakers, F., ROOT — A C++ framework for petabyte data storage, statistical analysis and visualization, Computer Physics Communications; Anniversary Issue; 180(12) (2009) 2499-2512.

Projections for dual radioisotope applications in PET imaging

Year 2021, , 722 - 727, 24.09.2021
https://doi.org/10.17776/csj.677410

Abstract

Positron emission tomography (PET) are widely accepted and used as an effective medical imaging method. We have studied on the dual radioisotopes C11 and Cu60 together by modifying the isotopes used in Standard cyclindirial PET through GATE imaging simulation. We scan the proper resolution intervals and the distances between the sources and present the differences in parameters such as full width at half maximum (FWHM), intensity and contrast. Applying statistical χ^2 method, we aim to show the significance limits of above parameteric differences in PET simulations. These results may help determine in which conditions the imaging devices can be used with dual isotope method in clinical applications. 

References

  • [1] Teksöz S., Müftüler FZB., Radioisotopes and Biomedical Applications in Nuclear Medicine, Nucl Med Semin, 5 (2019) 10-14.
  • [2] Andreyev, A., Sitek, A., & Celler, A. (2014). EM reconstruction of dual isotope PET using staggered injections and prompt gamma positron emitters, Medical Physics, 41(2) (2014) 022501.
  • [3] Andreyev, A., Celler, A., Dual-isotope PET using positron gamma emitters, Phys. Med. Biol. 56 (4539) (2011).
  • [4] Figueiras, F. P., et al., Simultaneous dual-tracer PET imaging of the ratbrain and its application in the study of cerebral ischemia, Mol. Imag. Biol., vol. 13(3) (2011) 500–510.
  • [5] Black, N. F. , Mcjames, S. and Kadrmas, D.J., Rapid multi-tracer PET tumor imaging with [18F] FDG and secondary shorter-lived tracers, IEEE Trans. Nucl. Sci., 56(5) (2009) 2750–2758.
  • [6] El Fakhri, G., Sitek, A. and Guerin, B., Simultaneous dual tracer PET using generalized factor analysis of dynamic sequences, Proc. Nucl.Sci. Symp. Conf. Rec., 15 (2006) 2128–2130.
  • [7] Jan, S. et al. , GATE: a simulation toolkit for PET and SPECT, Phys. Med. Biol., 49 (2004) 4543-4561.
  • [8] Brun, R., & Rademakers, F., ROOT — A C++ framework for petabyte data storage, statistical analysis and visualization, Computer Physics Communications; Anniversary Issue; 180(12) (2009) 2499-2512.
There are 8 citations in total.

Details

Primary Language English
Subjects Classical Physics (Other)
Journal Section Natural Sciences
Authors

Sinan Kuday 0000-0002-0116-5494

Yusuf Şengelen

Publication Date September 24, 2021
Submission Date January 20, 2020
Acceptance Date July 6, 2021
Published in Issue Year 2021

Cite

APA Kuday, S., & Şengelen, Y. (2021). Projections for dual radioisotope applications in PET imaging. Cumhuriyet Science Journal, 42(3), 722-727. https://doi.org/10.17776/csj.677410