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GATE / GEANT4 ile Dinamik Kaynaklar üzerinde SPECT Benzetimlerinin Doz Hesaplamaları

Year 2019, , 347 - 354, 30.06.2019
https://doi.org/10.17776/csj.534489

Abstract

SPECT çalışmalarının simülasyonları,
gelişen bilgisayar teknikleriyle birlikte tıbbi görüntülemede daha doğru
sonuçların elde edilebileceği gerçeğine dikkat çekmektedir. Sonuç olarak, canlı
dokulara zarar vermeden yüksek düzeyde istatistik elde etmek için gerçek
olaylara uygulanmadan önce tıbbi simülasyonların yardımıyla yeni fikirler veya
iyileştirmeler görselleştirilebilir. Bu çalışmada, GEANT4 simülasyonları
çerçevesinde geliştirilmiş GATE (a simulation toolkit for PET & SPECT)
yazılımının yetenekleri ile aktivite azalmaları, yer değiştirmeler ve dokuların
üst üste gelmeleri gibi etkilerin uygulamaları üzerine yoğunlaştık. Enerji
histogramları ve doz hesaplamaları, öntanımlı dokular kullanılarak ve ROOT
analiz yazılımı kullanılarak sanal verilerin analiz edilmesiyle elde edildi.
Sonuçlar, SPECT görüntülerde ve bunların spesifik parametrelere bağımlılıklarında
önemli bir bozulmaya neden olabilecek etkilerin büyüklüğünü göstermektedir.

References

  • Buck K. A., Nekolla S., Ziegler S., Beer A., Krause A. J., Herrmann K., Scheidhauer K., Wester H., Rummeny E. J., Schwaiger M., Drzezga A., SPECT/CT , J. Nucl. Med., 49 (8) (2008), 1305-1319.
  • Bybel B., Brunken R. C., DiFilippo F. P., Neumann D. R., Wu G., Cerqueira M. D., SPECT/CT Imaging: Clinical Utility of an Emerging Technology, Radiographics, 28(4) (2008), 1097-113.
  • Madsen, M.T., Recent advances in SPECT imaging., J Nucl. Med., 48(4)(2007), 661–673.
  • Groch, M.W., Erwin, W. D., SPECT in the year 2000: Basic Principles, J. Nucl. Med. Technol., 28 (4) (200), 233-44.
  • Habib, Z., Hasegawa, B., Determination of the Attenuation Map in Emission Tomography, J. Nucl. Med., 44 (2) (2003), 291-315.
  • Khalil M. M., Tremoleda J. L., Tamer B. Bayomy, and W. Gsell, Molecular SPECT Imaging: An Overview, International Journal of Molecular Imaging, 796025 (2011), 1-15
  • Müller J., Putora P. M., Schneider T., Zeisel C., Brutsche M., Baty F., Markus A., Kick J., Handheld single photon emission computed tomography (handheld SPECT) navigated video-assisted thoracoscopic surgery of computer tomography-guided radioactively marked pulmonary lesions, Interactive CardioVascular and Thoracic Surgery, 23- 3, (2016), 345–350.
  • Patton, J.A., Turkington T.G., SPECT/CT physical principles and attenuation correction., J. Nucl Med Technol., 36(1) (2008), 1-10.
  • Keenan, M. A., Stabin M. G., Segars W. P., Fernald M. J., RADAR Realistic Animal Model Series for Dose Assessment, J. Nucl. Med., 51(3) (2010), 471-6.
  • Jan, S., et. al., GATE - Geant4 Application for Tomographic Emission: a simulation toolkit for PET and SPECT, Phys Med Biol. , 49 (19) (2004), 4543–4561.
  • Arce P., Mendes P. R., Lagares J. I., GAMOS: a GEANT4-based Easy and Flexible Framework for Nuclear Geant4 Simulations, IEEE Proc. Nuc. Sci. Symp. Conf. Rec., 1 (2008), 3162 - 3168.
  • CERN-MEDICIS Collaboration, CERN-MEDICIS (Medical Isotopes Collected from ISOLDE): A New Facility, Appl. Sci., 4(2) (2014), 265-281.
  • http://www.opengatecollaboration.org/sites/default/files/GATE-UsersGuideV8.0.pdf

Dose Calculations of SPECT Simulations on Dynamical Targets with GATE / GEANT4

Year 2019, , 347 - 354, 30.06.2019
https://doi.org/10.17776/csj.534489

Abstract

References

  • Buck K. A., Nekolla S., Ziegler S., Beer A., Krause A. J., Herrmann K., Scheidhauer K., Wester H., Rummeny E. J., Schwaiger M., Drzezga A., SPECT/CT , J. Nucl. Med., 49 (8) (2008), 1305-1319.
  • Bybel B., Brunken R. C., DiFilippo F. P., Neumann D. R., Wu G., Cerqueira M. D., SPECT/CT Imaging: Clinical Utility of an Emerging Technology, Radiographics, 28(4) (2008), 1097-113.
  • Madsen, M.T., Recent advances in SPECT imaging., J Nucl. Med., 48(4)(2007), 661–673.
  • Groch, M.W., Erwin, W. D., SPECT in the year 2000: Basic Principles, J. Nucl. Med. Technol., 28 (4) (200), 233-44.
  • Habib, Z., Hasegawa, B., Determination of the Attenuation Map in Emission Tomography, J. Nucl. Med., 44 (2) (2003), 291-315.
  • Khalil M. M., Tremoleda J. L., Tamer B. Bayomy, and W. Gsell, Molecular SPECT Imaging: An Overview, International Journal of Molecular Imaging, 796025 (2011), 1-15
  • Müller J., Putora P. M., Schneider T., Zeisel C., Brutsche M., Baty F., Markus A., Kick J., Handheld single photon emission computed tomography (handheld SPECT) navigated video-assisted thoracoscopic surgery of computer tomography-guided radioactively marked pulmonary lesions, Interactive CardioVascular and Thoracic Surgery, 23- 3, (2016), 345–350.
  • Patton, J.A., Turkington T.G., SPECT/CT physical principles and attenuation correction., J. Nucl Med Technol., 36(1) (2008), 1-10.
  • Keenan, M. A., Stabin M. G., Segars W. P., Fernald M. J., RADAR Realistic Animal Model Series for Dose Assessment, J. Nucl. Med., 51(3) (2010), 471-6.
  • Jan, S., et. al., GATE - Geant4 Application for Tomographic Emission: a simulation toolkit for PET and SPECT, Phys Med Biol. , 49 (19) (2004), 4543–4561.
  • Arce P., Mendes P. R., Lagares J. I., GAMOS: a GEANT4-based Easy and Flexible Framework for Nuclear Geant4 Simulations, IEEE Proc. Nuc. Sci. Symp. Conf. Rec., 1 (2008), 3162 - 3168.
  • CERN-MEDICIS Collaboration, CERN-MEDICIS (Medical Isotopes Collected from ISOLDE): A New Facility, Appl. Sci., 4(2) (2014), 265-281.
  • http://www.opengatecollaboration.org/sites/default/files/GATE-UsersGuideV8.0.pdf
There are 13 citations in total.

Details

Primary Language English
Journal Section Natural Sciences
Authors

Sinan Kuday 0000-0002-0116-5494

Publication Date June 30, 2019
Submission Date March 1, 2019
Acceptance Date March 27, 2019
Published in Issue Year 2019

Cite

APA Kuday, S. (2019). Dose Calculations of SPECT Simulations on Dynamical Targets with GATE / GEANT4. Cumhuriyet Science Journal, 40(2), 347-354. https://doi.org/10.17776/csj.534489