EN
A new spectrophotometric study with ortho hydroxy schiff base for the determination of aluminum in drug
Abstract
In this study, a Schiff base called (E)-2-((2- hydroxy -3- methoxy benzylidene)amino)-5- methylphenol (L) was used as a ligand. Spectrophotometric properties of the ligand have been defined and the optimum conditions for determining aluminium by complex by UV-Vis. spectrophotometry. The absorbance of Al(III)-L complex obeys Beer’s law between 1.4 µg mL–1 and 13.5 µg mL–1 for the aluminium in the optimum conditions. Under optimum conditions, the determination of aluminium in Kompensan® drug was done successfully. The LOD and LOQ values of the developed method were 0.01139 μg mL-1 and 0.0345 μg mL-1, respectively for the ligand.
Keywords
Supporting Institution
Anadolu Üniversitesi
Project Number
1509F633
Thanks
We kindly acknowledge to Anadolu University Scientific Research Projects (No:1509F633) for its support to this study.
References
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Details
Primary Language
English
Subjects
-
Journal Section
Research Article
Publication Date
June 25, 2020
Submission Date
February 23, 2020
Acceptance Date
June 5, 2020
Published in Issue
Year 2020 Volume: 41 Number: 2