Research Article

A new spectrophotometric study with ortho hydroxy schiff base for the determination of aluminum in drug

Volume: 41 Number: 2 June 25, 2020
EN

A new spectrophotometric study with ortho hydroxy schiff base for the determination of aluminum in drug

Abstract

In this study, a Schiff base called (E)-2-((2- hydroxy -3- methoxy benzylidene)amino)-5- methylphenol (L) was used as a ligand. Spectrophotometric properties of the ligand have been defined and the optimum conditions for determining aluminium by complex by UV-Vis. spectrophotometry. The absorbance of Al(III)-L complex obeys Beer’s law between 1.4 µg mL–1 and 13.5 µg mL–1 for the aluminium in the optimum conditions. Under optimum conditions, the determination of aluminium in Kompensan® drug was done successfully. The LOD and LOQ values of the developed method were 0.01139 μg mL-1 and 0.0345 μg mL-1, respectively for the ligand.

Keywords

Supporting Institution

Anadolu Üniversitesi

Project Number

1509F633

Thanks

We kindly acknowledge to Anadolu University Scientific Research Projects (No:1509F633) for its support to this study.

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Publication Date

June 25, 2020

Submission Date

February 23, 2020

Acceptance Date

June 5, 2020

Published in Issue

Year 2020 Volume: 41 Number: 2

APA
Güray, T., Ercengiz, D., & Uysal, Ü. D. (2020). A new spectrophotometric study with ortho hydroxy schiff base for the determination of aluminum in drug. Cumhuriyet Science Journal, 41(2), 456-461. https://doi.org/10.17776/csj.693029

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