Application of Heterocyclic Compounds as Catalysts in Suzuki-Miyaura Cross-Coupling Reaction

Senem Akkoç

doi:10.17776/csj.613060

TR EN

Application of Heterocyclic Compounds as Catalysts in Suzuki-Miyaura Cross-Coupling Reaction

Abstract

Four different benzimidazolium salts (1-4) were prepared in three steps at 80 ^oC and their structures were elucidated using spectroscopic methods. The compounds (1-4) obtained were tested in in situ medium as catalyst in the carbon-carbon (C-C) bond formation reactions of two different boronic acid derivatives with various aryl halides in the presence of palladium acetate (PdOAc)₂ and sodium tertiarybutoxide (NaOBu^t) as a base. With this reaction, four coupling products (5-8) were synthesized in different yields ranging from 11 to 93%. Compound 2 from the carbene precursors tested in the Suzuki-Miyaura cross-coupling reaction was found to be a more effective catalyst candidate than others.

Keywords

Suzuki-Miyaura coupling reaction,Benzimidazolium salt, Catalyst

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Senem Akkoç ^*
0000-0002-1260-9425
Türkiye

Publication Date

December 31, 2019

Submission Date

August 29, 2019

Acceptance Date

November 19, 2019

Published in Issue

Year 2019 Volume: 40 Number: 4

DOI

https://doi.org/10.17776/csj.613060

IZ

https://izlik.org/JA75GX47JR

Cite

RIS / Bibtex

APA

Akkoç, S. (2019). Application of Heterocyclic Compounds as Catalysts in Suzuki-Miyaura Cross-Coupling Reaction. Cumhuriyet Science Journal, 40(4), 854-859. https://doi.org/10.17776/csj.613060

Cited By

Investigation of structural, spectral, electronic, and biological properties of 1,3-disubstituted benzimidazole derivatives

Journal of Molecular Structure

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Importance of some factors on the Suzuki‐Miyaura cross‐coupling reaction

Journal of the Chinese Chemical Society

https://doi.org/10.1002/jccs.202000351

Application of Heterocyclic Compounds as Catalysts in Suzuki-Miyaura Cross-Coupling Reaction

Suzuki-Miyaura Çapraz Eşleşme Reaksiyonunda Katalizör Olarak Heterosiklik Bileşiklerin Uygulanması

Öz

Anahtar Kelimeler

Application of Heterocyclic Compounds as Catalysts in Suzuki-Miyaura Cross-Coupling Reaction

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Investigation of structural, spectral, electronic, and biological properties of 1,3-disubstituted benzimidazole derivatives

Importance of some factors on the Suzuki‐Miyaura cross‐coupling reaction