Electrochemical Detection of Epinephrine in The Presence of Ascorbic Acid at Poly (p-Aminobenzene Sulfonic Acid) Modified Sensor

Şevket Zişan Bilge Yağcı; Ebru Kuyumcu Savan; Gamze Erdoğdu

doi:10.17776/csj.426874

TR EN

Poli (p-Aminobenzen Sülfonik Asit) Modifiye Sensöründe Askorbik Asit Varlığında Epinefrinin Elektrokimyasal Tayini

Öz

Poli (p-aminobenzen sülfonik asit, ABSA) modifiye sensör ile askorbik asit varlığında epinefrinin (EP) hızlı, güvenilir ve duyarlı bir şekilde seçici ve eş zamanlı voltametrik tayini gerçekleştirildi. Camsı karbon elektrot, ABSA ile 0.1 M KCl çözeltisi içerisinde çevrimli voltametri tekniğiyle başarılı bir şekilde modifiye edildi. Polimerik ince film ile modifiye edilen sensör, EP ve askorbik asitin (AA) yükseltgenmesine karşı mükemmel elektro-katalitik etki göstermiştir. Sonuçlar, her iki türün oksidasyon potansiyeli ve oksidasyon pik akım yanıtlarının önemli derecede iyileştiğini göstermiştir. Modifiye sensör, optimum koşullar altında EP tayinine karşı 5.0–53.2 µM derişim aralığında 50 nM tayin sınırı ile mükemmel cevap göstermiştir. Farmasötik preparatta ve kan serumunda gerçekleştirilen gerçek numune analizlerinde geri kazanım değerleri % 98.4 - 77.3 di. Elde edilen sonuçlar, modifiye sensörün AA varlığında EP’in saptanmasında uygulanabileceğini göstermiştir. Önerilen sensörün, yüksek seçicilik, tekrarlanabilirlik, tekrarüretilebilirlik ve uzun-süreli kararlılık özelliklerinden ve farmasötik ve biyolojik örneklerde elde edilen yüksek geri kazanım değerlerinden dolayı rutin analizlerde uygulanabilecek olması umut vericidir.

Anahtar Kelimeler

Epinefrin,p-aminobenzen sülfonik asit,sensör,voltametri

References

[1]. Tavana, T., Khalilzadeh, M.A., Karimi-Maleh, H., Ensafi, A.A., Beitollahi, H. and Zareyee, D., Sensitive voltammetric determination of epinephrine in the presence of acetaminophen at a novel ionic liquid modified carbon nanotubes paste electrode, J. Mol. Liq., 168 (2012) 69–74.
[2]. Jackson, L., Williams, F.L.R., Burchell, A., Coughtrie M.W.H. and Hume, R., Plasma catecholamines and the counterregulatory responses to hypoglycemia in infants: A critical role for epinephrine and cortisol, J. Clin. Endocrinol. Metab., 89-12 (2004) 6251–6256.
[3]. Bergquist, J., Ciubisz, A., Kaczor, A. and Silberring, J. Catecholamines and methods for their identification and quantitation in biological tissues and fluids. J. Neurosci. Meth. 113 (2002) 1–13.
[4]. Martinez-Quintana, E. et al. Acute myocardial infarction secondary to catecholamine release owing to cocaine abuse and pheochromocytoma crisis. Int. J. Endocrinol. Metab., 11 (2013) 48–51.
[5]. Beitollahi, H., Ardakani, M.M., Ganjipour, B. and Naeimi, H. Novel 2,2′-[1,2-ethanediylbis(nitriloethylidyne)]-bis-hydroquinone double-wall carbon nanotube paste electrode for simultaneous determination of epinephrine, uric acid and folic acid. Biosens. Bioelectron., 24 (2008) 362–368.
[6]. Jin, G.-P., Lin, X.-Q. and Gong, J. Novel choline and acetylcholine modified glassy carbon electrodes for simultaneous determination of dopamine, serotonin and ascorbic acid. J. Electroanal. Chem., 569 (2004) 135–142.
[7]. Mazloum-Ardakani, M., Talebi, A., Naeimib, H. and Sheikh-Mohseni, M.A. Electrocatalysis of epinephrine by TiO2 nanoparticles and 2,20-[1,7- hepthandiylbis(nitriloethylidyne)]-bis-hydroquinone modified carbon paste electrode. Anal. Methods, 3 (2011) 2328–2333.
[8]. Mazloum-Ardakani, M. et al. Simultaneous determination of epinephrine and acetaminophen concentrations using a novel carbon paste electrode prepared with 2,2′-[1,2 butanediylbis(nitriloethylidyne)]-bis-hydroquinone and TiO2nanoparticles. Colloids Surfaces B Biointerfaces 76 (2010)82–87.

[9]. Wong, D.L., Tai, T.C., Wong-Faull, D.C., Claycomb, R. and Kvetňanský, R. Adrenergic responses to stress: Transcriptional and post-transcriptional changes. Ann. N. Y. Acad. Sci., 1148 (2008) 249–256.
[10]. Carbone, M., Nesticò, A., Bellucci, N., Micheli, L. and Palleschi, G. Enhanced performances of sensors based on screen printed electrodes modified with nanosized NiO particles. Electrochim. Acta, 246 (2017) 580–587.
[11]. Zhang, W., He, L., Gu, Y., Liu, X. and Jiang, S. Effect of ionic liquids as mobile phase additives on retention of catecholamines in reversed-phase high-performance liquid chromatography. Anal. Lett., 36 (2003) 827–838.
[12]. Babaei, A., Sohrabi, M. and Afrasiabi, M. A Sensitive Simultaneous Determination of Epinephrine and Piroxicam Using a Glassy Carbon Electrode Modified with a Nickel Hydroxide Nanoparticles/Multiwalled Carbon Nanotubes Composite. Electroanalysis, 24 (2012) 2387–2394.
[13]. Niu, L.M., Luo, H.Q. and Li, N.B. Electrochemical behavior of epinephrine at a penicillamine self-assembled gold electrode, and its analytical application. Microchim. Acta 150 (2005) 87–93.
[14]. Wang, L. et al. Electrochemical behavior and determination of epinephrine at a penicillamine self-assembled gold electrode. Int. J. Electrochem. Sci., 1 (2006) 238–249.
[15]. Niu, L.M., Luo, H.Q. and Li, N.B. Electrochemical behavior of uric acid at a meso-2,3-dimercaptosuccinic acid self-assembled gold electrode. Instrum. Sci. Technol., 35 (2007) 59–73.
[16]. Fang, C., Tang, X. and Zhou, X. Preparation of Poly(malachite green) Modified Electrode and the Determination of Dopamine and Ascorbic Acid. Anal. Sci., 15 (1999) 41–46.
[17]. Kumar, S.S., Mathiyarasu, J., Phani, K.L., Jain, Y.K. and Yegnaraman, V. Determination of uric acid in the presence of ascorbic acid using poly(3,4-ethylenedioxythiophene)-modified electrodes. Electroanalysis, 17 (2005) 2281–2286.
[18]. Zhao, Y., Bai, J., Wang, L., Huang, P. and Wang, H. Simultaneous Electrochemical Determination of Uric Acid and Ascorbic Acid Using L -Cysteine Self-Assembled Gold Electrode. Int. J. Electrochem. Sci., 1 (2006) 363–371.
[19]. Yang, Z., Hu, G., Chen, X., Zhao, J. and Zhao, G. The nano-Au self-assembled glassy carbon electrode for selective determination of epinephrine in the presence of ascorbic acid. Colloids Surfaces B Biointerfaces, 54 (2007) 230–235.
[20]. Wang, H.-S., Li, T.-H., Jia, W.-L. and Xu, H.-Y. Highly selective and sensitive determination of dopamine using a Nafion/carbon nanotubes coated poly(3-methylthiophene) modified electrode. Biosens. Bioelectron., 22 (2006) 664–669.
[21]. Savan, E.K. and Erdoğdu, G. Determination of 3,4-dihydroxyphenylacetic acid in the presence of ascorbic acid and uric acid at poly(p-aminobenzene sulfonic acid) conducting polymer electrode. Polym. Bull., 74-10 (2017) 4349-4360.
[22]. Erdoğdu, G. and Mutlu, M.M. Selective Detection of Dopamine in the Presence of Ascorbic Acid at Poly (m-Aminobenzene Sulfonic Acid). Am. J. Anal. Chem., 02 (2011) 582–588.
[23]. Jin, G., Zhang, Y. and Cheng, W. Poly(p-aminobenzene sulfonic acid)-modified glassy carbon electrode for simultaneous detection of dopamine and ascorbic acid. Sensors Actuators B Chem., 107 (2005) 528–534.
[24]. Ren, W., Luo, H.Q. and Li, N.B. Electrochemical behavior of epinephrine at a glassy carbon electrode modified by electrodeposited films of caffeic acid. Sensors, 6 (2006) 80–89.
[25]. Wierzbicka, E. and Sulka, G.D. Nanoporous spongelike Au–Ag films for electrochemical epinephrine sensing. J. Electroanal. Chem., 762 (2016) 43–50.
[26]. Shahrokhian, S., Ghalkhani, M. and Amini, M.K. Application of carbon-paste electrode modified with iron phthalocyanine for voltammetric determination of epinephrine in the presence of ascorbic acid and uric acid. Sensors Actuators, B Chem., 137 (2009) 669–675.
[27]. Bakir C.C., Preparation and characterization of metal nano particles modified carbon nanotube and polymer film electrodes and their analytical applications. Ege Üniversitesi, Fen Bilimleri Enstitüsü, (2010).
[28]. Rostami, A. and Taylor, M.S. Polymers for anion recognition and sensing. Macromol. Rap. Commun., 33 (2012) 21-34.
[29]. Liu, H., Zhao, G., Wen, L. and Ye, B. Simultaneous voltammetric determination of epinephrine and serotonin at a p-tetra-butyl calix [6] arene-L-Histidine chemically modified electrode. J. Anal. Chem., 61 (2006) 1104–1107.
[30]. Gong, J. and Lin, X. A glassy carbon supported bilayer lipid-like membrane of 5,5-ditetradecyl-2-(2-trimethyl-ammonioethyl)-1,3-dioxane bromide for electrochemical sensing of epinephrine. Electrochim. Acta, 49 (2004) 4351–4357.
[31]. Ren, W., Luo, H.Q. and Li, N. B. Simultaneous voltammetric measurement of ascorbic acid, epinephrine and uric acid at a glassy carbon electrode modified with caffeic acid. Biosens. Bioelectron., 21 (2006) 1086–1092.
[32]. Yogeswaran, U., Thiagarajan, S. and Chen, S.-M. Nanocomposite of functionalized multiwall carbon nanotubes with nafion, nano platinum, and nano gold biosensing film for simultaneous determination of ascorbic acid, epinephrine, and uric acid. Anal. Biochem., 365 (2007) 122–131.
[33]. Cheng, W., Jin, G. and Zhang, Y. Electrochemical Characteristics of Poly ( o -Aminobenzoic Acid ) Modified Glassy-Carbon Electrode and Its Electrocatalytic Activity towards Oxidation of Epinephrine . Russ. J. Electrochem., 41 (2005) 940–945.
[34]. Taylor, P., He, Y. Bin, Luo, H. Q. and Li, N. B. Electrochemical Behavior of Epinephrine at Two ‐ Component Self ‐ Assembled Monolayer of meso ‐ 2 , 3 ‐ Dimercaptosuccinic Acid and Penicillamine on Gold Electrode. Instr. Sci. Technol., 35 (2007) 163–175.

Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Şevket Zişan Bilge Yağcı
0000-0002-6064-3177
Türkiye

Ebru Kuyumcu Savan
0000-0002-8851-0907
Türkiye

Gamze Erdoğdu ^*
0000-0002-8114-6946
Türkiye

Publication Date

December 24, 2018

Submission Date

May 25, 2018

Acceptance Date

December 6, 2018

Published in Issue

Year 1970 Volume: 39 Number: 4

DOI

https://doi.org/10.17776/csj.426874

IZ

https://izlik.org/JA73CY73FF

Cite

RIS / Bibtex

APA

Yağcı, Ş. Z. B., Kuyumcu Savan, E., & Erdoğdu, G. (2018). Electrochemical Detection of Epinephrine in The Presence of Ascorbic Acid at Poly (p-Aminobenzene Sulfonic Acid) Modified Sensor. Cumhuriyet Science Journal, 39(4), 1025-1035. https://doi.org/10.17776/csj.426874

Electrochemical Detection of Epinephrine in The Presence of Ascorbic Acid at Poly (p-Aminobenzene Sulfonic Acid) Modified Sensor

Poli (p-Aminobenzen Sülfonik Asit) Modifiye Sensöründe Askorbik Asit Varlığında Epinefrinin Elektrokimyasal Tayini

Öz

Anahtar Kelimeler