Histopathological Effects of Fonofos on Gills of Zebrafish (Danio rerio)

Sezgi Arman; Sema İşisağ Üçüncü

doi:10.17776/csj.424499

TR EN

Histopathological Effects of Fonofos on Gills of Zebrafish (Danio rerio)

Abstract

Organophosphate pesticides are commonly used to increase agricultural efficiency worldwide. However, it has been proved that these chemicals generally do not show target specificity and non-target vertebrate organisms are adversely affected by pesticide exposure. The aim of the present study was to examine the potential harmful effects of fonofos, an organophosphate insecticide, on the gill tissues of zebrafish (Danio rerio). Adult zebrafish were exposed to 1, 2 and 4 mg/L fonofos for 96 hours. Gill tissues were removed, fixed with Bouin’s fluid and embedded in paraffin. 5 µm serial sections were stained with hematoxylin-eosin, Gomori trichrome or periodic acid-Schiff. Samples were investigated by light microscopy and histological alterations were compared with the 0.1% dimethyl sulfoxide (DMSO) exposed solvent control samples. Fonofos caused epithelial lifting, curling of secondary lamellae, desquamation, epithelial hyperplasia, and lamellar fusion in the gills. Gills showed distinct histopathological changes through fonofos exposure. It was determined that fonofos is a threat to non-target organisms living in aquatic ecosystems.

Keywords

Fonofos,insecticide,gill,histopathology,zebrafish,Danio rerio

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Sezgi Arman ^*
0000-0002-4247-0639
Türkiye

Sema İşisağ Üçüncü
0000-0002-2739-4009

Publication Date

March 22, 2019

Submission Date

May 17, 2018

Acceptance Date

January 22, 2019

Published in Issue

Year 2019 Volume: 40 Number: 1

DOI

https://doi.org/10.17776/csj.424499

IZ

https://izlik.org/JA67CD48AH

Cite

RIS / Bibtex

APA

Arman, S., & İşisağ Üçüncü, S. (2019). Histopathological Effects of Fonofos on Gills of Zebrafish (Danio rerio). Cumhuriyet Science Journal, 40(1), 35-41. https://doi.org/10.17776/csj.424499

Cited By

Dietary Nigella sativa oil confers protection against diazinon toxicity in nile tilapia (Oreochromis niloticus): A detoxification-based approach

Veterinary Research Communications

https://doi.org/10.1007/s11259-025-10861-2

Histopathological Effects of Fonofos on Gills of Zebrafish (Danio rerio)

Fonofos’un Zebra Balığı (Danio rerio) Solungaçlarındaki Histopatolojik Etkileri

Öz

Anahtar Kelimeler

Histopathological Effects of Fonofos on Gills of Zebrafish (Danio rerio)

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Dietary Nigella sativa oil confers protection against diazinon toxicity in nile tilapia (Oreochromis niloticus): A detoxification-based approach