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Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders
Abstract
In this study, gamma rays were applied to the sulfadimethoxine, pyrazinamide, and chloramphenicol in the dose range of 1-15 kilogray, in order to
detect radiosensitivity of paramagnetic species, which are formed after
irradiation by electron paramagnetic resonance spectroscopy. Firstly, the intensities of
electron paramagnetic resonance signals of the samples as a function of the
microwave power were investigated at room temperature. While no signal was
obtained from the unirradiated samples, the irradiated samples exhibited
significant spectra. Additionally, the time dependency of the samples was
analyzed to study the stability of the radicals.
Keywords
References
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- [6]. Basly J.P., Bernard M. and Basly I., Electron Spin Resonance Detection of Radiosterilization of Pharmaceuticals: Application to four nitrofurans, Analyst, 123 (1998) 1753-1756.
- [7]. Basly J.P. and Bernard M., Radio Sterilization Dosimetry by ESR Spectroscopy: Ritodrine Hydrochloride and Comparison with other Sympathomimetics, Int. J. Pharmaceut., 149 (1997) 85-91.
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Details
Primary Language
English
Subjects
-
Journal Section
Research Article
Publication Date
June 29, 2018
Submission Date
February 5, 2018
Acceptance Date
May 3, 2018
Published in Issue
Year 2018 Volume: 39 Number: 2
APA
Osmanoğlu, Ş., & Sütçü, K. (2018). Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders. Cumhuriyet Science Journal, 39(2), 380-388. https://doi.org/10.17776/csj.390570
AMA
1.Osmanoğlu Ş, Sütçü K. Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders. CSJ. 2018;39(2):380-388. doi:10.17776/csj.390570
Chicago
Osmanoğlu, Şemsettin, and Kerem Sütçü. 2018. “Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders”. Cumhuriyet Science Journal 39 (2): 380-88. https://doi.org/10.17776/csj.390570.
EndNote
Osmanoğlu Ş, Sütçü K (June 1, 2018) Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders. Cumhuriyet Science Journal 39 2 380–388.
IEEE
[1]Ş. Osmanoğlu and K. Sütçü, “Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders”, CSJ, vol. 39, no. 2, pp. 380–388, June 2018, doi: 10.17776/csj.390570.
ISNAD
Osmanoğlu, Şemsettin - Sütçü, Kerem. “Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders”. Cumhuriyet Science Journal 39/2 (June 1, 2018): 380-388. https://doi.org/10.17776/csj.390570.
JAMA
1.Osmanoğlu Ş, Sütçü K. Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders. CSJ. 2018;39:380–388.
MLA
Osmanoğlu, Şemsettin, and Kerem Sütçü. “Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders”. Cumhuriyet Science Journal, vol. 39, no. 2, June 2018, pp. 380-8, doi:10.17776/csj.390570.
Vancouver
1.Şemsettin Osmanoğlu, Kerem Sütçü. Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders. CSJ. 2018 Jun. 1;39(2):380-8. doi:10.17776/csj.390570