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Synthesis and Biological Evaluation of Novel 5,8-Dibromo-2-N-substituted-1,4-Naphthoquinone Derivatives as Potential Antimicrobial Agents
Abstract
The seven 5,8-dibromo-2-N-substituted-1,4-naphthoquinone
derivatives have been synthesized and tested for their in vitro antimicrobial
activities. The results suggest that the synthesized 2-N-substituted-1,4-naphthoquinones
have high antimicrobial activity. The diffusion capacities of the compounds are
also important for the determination of the antimicrobial activities; 2c, 2f and 2g have been
shown to be promising compounds for future studies.
Keywords
References
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Details
Primary Language
English
Subjects
Pharmacology and Pharmaceutical Sciences
Journal Section
Research Article
Publication Date
September 30, 2018
Submission Date
November 9, 2017
Acceptance Date
July 21, 2018
Published in Issue
Year 2018 Volume: 39 Number: 3
APA
Berkil Akar, K., Mercan, E., Eran, B., & Çadırcı, B. H. (2018). Synthesis and Biological Evaluation of Novel 5,8-Dibromo-2-N-substituted-1,4-Naphthoquinone Derivatives as Potential Antimicrobial Agents. Cumhuriyet Science Journal, 39(3), 608-614. https://doi.org/10.17776/csj.350308