Comparative Chemical Composition and Antimicrobial Activities of The Essential Oils and Solvent Extracts of The Flower, Leaf, And Stem of Epilobium angustifolium Growing in Türkiye

Büşra Korkmaz; Gözde Bozdal; Şeyma Arıcı Tüfekçi; Büşra Şahin; Elif Öztürk; Şengül Alpay Karaoğlu; Serdar Makbul; Nurettin Yaylı

doi:10.17776/csj.1591654

TR EN

183 / 5,000 Türkiye'de Yetişen Epilobium angustifolium'un Çiçeği, Yaprağı ve Gövdesi İçin Esansiyel Yağların ve Çözücü Ekstraktlarının Karşılaştırmalı Kimyasal Bileşimi ve Antimikrobiyal Aktiviteleri

Öz

Epilobium angustifolium L.'nin çiçeğinden, yaprağından ve gövdesinden elde edilen uçucu yağların (EO'lar) ve katı faz mikroekstraksiyonunun (SPME) uçucu organik bileşikleri (VOC'ler) GC-FID/MS ile analiz edildi. EO'lar ve SPME'ler esas olarak, başlıca bileşik sınıfları olan monoterpenler ve aldehitlerden oluşur. Limonenin çiçekte (HD: %42,9'a karşı SPME: %95,5), yaprakta (HD: %60,3'e karşı SPME: %4,7) ve gövdede (HD: %49,06'ya karşı SPME: %93,6) başlıca bileşik olduğu bulundu. E. angustifolium'un EO'larının ve çözücü özütlerinin (n-hekzan, asetonitril ve metanol) antimikrobiyal aktivitesi dokuz mikroorganizmaya karşı in vitro tarandı. Yaprağın EO'su Mycobacterium smegmatis'e karşı en iyi aktiviteyi (10,2 µg/mL MİK) gösterdi. Tüm EO'lar ve çözücü özütleri 10,2-1300,0 µg/mL MİK değerleri aralığında Staphylococcus aureus, Bacillus cereus ve M. smegmatis'e karşı orta düzeyde aktivite gösterdi. En iyi antibakteriyel aktivite, sapın n-hekzan özütü ve çiçek örneklerinin metanol özütündeki S. aureus ve B. cereus'a karşı gözlendi.

Anahtar Kelimeler

Comparative Chemical Composition and Antimicrobial Activities of The Essential Oils and Solvent Extracts of The Flower, Leaf, And Stem of Epilobium angustifolium Growing in Türkiye

Abstract

Volatile organic compounds (VOCs) of essential oils (EOs) and solid phase microextract (SPME) obtained from the flower, leaf, and stem of Epilobium angustifolium L. were analyzed by GC-FID/MS. The EOs and SPMEs consist mainly of monoterpenes and aldehydes, which are major classes of compounds. Limonene was found to be a major compound in flower (HD: 42.9% vs. SPME: 95.5%), in leaf (HD: 60.3% vs. SPME: 4.7%), and in stem (HD: 49.06% vs. SPME: 93.6%). The antimicrobial activity of EOs and the solvent extracts (n-hexane, acetonitrile, and methanol) of E. angustifolium were screened in vitro against nine microorganisms. The EO of the leaf showed the best activity (10.2 µg/mL MIC) against Mycobacterium smegmatis. All the EOs and the solvent extracts gave moderate activity against the Staphylococcus aureus, Bacillus cereus, and M. smegmatis within the range of 10.2-1300.0 µg/mL MIC values. The best antibacterial activity was observed against S. aureus and B. cereus in the n-hexane extract of stem and methanol extract of flower samples.

Keywords

Project Number

KTU-BAP (8881 and 6714)

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Details

Primary Language

English

Subjects

Pharmacognosy , Natural Products and Bioactive Compounds

Journal Section

Research Article

Authors

Büşra Korkmaz ^*
0000-0002-3747-8855
Türkiye

Gözde Bozdal
0000-0003-1248-7912
Türkiye

Şeyma Arıcı Tüfekçi
0009-0001-4791-8287
Türkiye

Büşra Şahin
0000-0002-2727-9801
Türkiye

Elif Öztürk
0000-0002-0809-6145
Türkiye

Şengül Alpay Karaoğlu
0000-0003-1047-8350
Türkiye

Serdar Makbul
0000-0001-8798-0926
Türkiye

Nurettin Yaylı
0000-0003-4174-3014
Türkiye

Publication Date

March 25, 2025

Submission Date

November 28, 2024

Acceptance Date

February 12, 2025

Published in Issue

Year 2025 Volume: 46 Number: 1

DOI

https://doi.org/10.17776/csj.1591654

IZ

https://izlik.org/JA77KY24WT

Cite

RIS / Bibtex

APA

Korkmaz, B., Bozdal, G., Arıcı Tüfekçi, Ş., Şahin, B., Öztürk, E., Alpay Karaoğlu, Ş., Makbul, S., & Yaylı, N. (2025). Comparative Chemical Composition and Antimicrobial Activities of The Essential Oils and Solvent Extracts of The Flower, Leaf, And Stem of Epilobium angustifolium Growing in Türkiye. Cumhuriyet Science Journal, 46(1), 27-34. https://doi.org/10.17776/csj.1591654