In Vitro Tyrosinase and Collagenase Inhibitory and Antioxidant Potential of Smyrnium rotundifolium Mill. and Euphorbia virgata Waldst.&Kit. from Türkiye

Eda Sönmez Gürer; Ayşe Esra Karadağ; Rengin Baydar; Melek Demirel

doi:10.17776/csj.1568111

EN

In Vitro Tyrosinase and Collagenase Inhibitory and Antioxidant Potential of Smyrnium rotundifolium Mill. and Euphorbia virgata Waldst.&Kit. from Türkiye

Abstract

Antioxidants help prevent signs of aging and skin tone inequalities by protecting our skin from free radicals. High tyrosinase inhibition has a whitening effect on the skin, while collagenase inhibition has an anti-sagging effect on the skin. Antioxidant activity and tyrosinase/collagenase enzyme inhibition capacities have mutually supporting effects. The aim of this study was to determine the antioxidant activities, tyrosinase and collagenase inhibitory potentials of ethanol extracts of two medicinal plants from Turkey (Smyrnium rotundifolium and Euphorbia virgata). In the study, 6 different reference substances and their chemical contents were investigated. Myricetin, quercetin and kaempferol were observed in S. rotundifolium extract, and quercetin was observed in E. virgata extract. According to the antioxidant capacity results measured by both analyses; S. rotundifolium (IC50 DPPH•: 4.9±0.15 µg/mL, IC50 ABTS•+: 4.3±0.2 µg/mL) and E. virgata (IC50 DPPH•: 4.6±0.11 µg/mL, IC50 ABTS•+: 4.1±0.13 µg/mL) extracts were observed to have antioxidant capacities similar to each other. It was determined that S. rotundifolium had higher anti-collagenase (27.9±0.13% inhibition) and anti-tyrosinase (11.1±0.14% inhibition) activities compared to E. virgata extract. These results showed us that S. rotundifolium can be considered as a strong candidate for the management of epidermal hyperpigmentation and skin elasticity and deserves further study.

Keywords

References

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Details

Primary Language

English

Subjects

Plant Biochemistry , Botany (Other)

Journal Section

Research Article

Authors

Eda Sönmez Gürer ^*
0000-0003-0319-6312
Türkiye

Ayşe Esra Karadağ
0000-0002-3412-0807
Türkiye

Rengin Baydar
0009-0008-3754-0293
Türkiye

Melek Demirel
0000-0002-8477-1122
Türkiye

Publication Date

December 30, 2024

Submission Date

October 19, 2024

Acceptance Date

December 19, 2024

Published in Issue

Year 2024 Volume: 45 Number: 4

DOI

https://doi.org/10.17776/csj.1568111

IZ

https://izlik.org/JA64GS67FT

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RIS / Bibtex

APA

Sönmez Gürer, E., Karadağ, A. E., Baydar, R., & Demirel, M. (2024). In Vitro Tyrosinase and Collagenase Inhibitory and Antioxidant Potential of Smyrnium rotundifolium Mill. and Euphorbia virgata Waldst.&Kit. from Türkiye. Cumhuriyet Science Journal, 45(4), 756-762. https://doi.org/10.17776/csj.1568111

Öz

In Vitro Tyrosinase and Collagenase Inhibitory and Antioxidant Potential of Smyrnium rotundifolium Mill. and Euphorbia virgata Waldst.&Kit. from Türkiye

Abstract

Keywords

References

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Journal Section

Authors

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Acceptance Date

Published in Issue

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