Investigation of Anti-CA II Antibodies in The Sera of Helicobacter Pylori Infected Patients

Sibel Yiğit Alaşalvar; Elif Şahin; Eşref Edip Keha

doi:10.17776/csj.1549477

EN

Investigation of Anti-CA II Antibodies in The Sera of Helicobacter Pylori Infected Patients

Abstract

It has been postulated that there may be a correlation between gastric infection caused by Helicobacter pylori (H. Pylori) and autoimmune pancreatitis (AIP). An increase in carbonic anhydrase II (CA II) autoantibodies was found in the sera of patients with AIP and it was suggested that measurement of these autoantibodies could be used in the diagnosis of AIP. In this study, the levels of CA II autoantibodies have been determined in the sera of the patients with H. pylori-infected gastritis and gastric ulcer. Anti-CA II antibody levels in the sera of these individuals were measured by ELISA method. There were significant differences between the control group and the H. pylori-infected gastric ulcer group and the gastritis group. When the H. pylori-infected and non-infected gastric ulcer and gastritis groups were compared, it became apparent that there were notable differences. The results indicated that the CA II antibodies in the sera of the H. pylori-infected patients were present at a rate of 8.3%. This led to the conclusion that CA II antibodies may not be a reliable marker for H. pylori infection. However, the investigation did demonstrate a clear increase in the levels of CA II antibodies for H. pylori-infected patients.

Keywords

References

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Details

Primary Language

English

Subjects

Microbiology (Other) , Medical Biochemistry - Proteins, Peptides and Proteomics

Journal Section

Research Article

Authors

Sibel Yiğit Alaşalvar
0000-0003-4472-7554
Türkiye

Elif Şahin ^*
0000-0001-5864-9548
Türkiye

Eşref Edip Keha
0000-0002-2271-5811
Türkiye

Publication Date

March 25, 2025

Submission Date

September 17, 2024

Acceptance Date

February 12, 2025

Published in Issue

Year 2025 Volume: 46 Number: 1

DOI

https://doi.org/10.17776/csj.1549477

IZ

https://izlik.org/JA98SY76WF

Cite

RIS / Bibtex

APA

Yiğit Alaşalvar, S., Şahin, E., & Keha, E. E. (2025). Investigation of Anti-CA II Antibodies in The Sera of Helicobacter Pylori Infected Patients. Cumhuriyet Science Journal, 46(1), 22-26. https://doi.org/10.17776/csj.1549477

Öz

Investigation of Anti-CA II Antibodies in The Sera of Helicobacter Pylori Infected Patients

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite