Electrochemical Oxidation of Ranitidine using a Boron-Doped Diamond Electrode in the Presence of Anionic Surfactant: A Comprehensive Investigation

Hasret Subak; Pınar Talay Pınar

doi:10.17776/csj.1423273

EN

Electrochemical Oxidation of Ranitidine using a Boron-Doped Diamond Electrode in the Presence of Anionic Surfactant: A Comprehensive Investigation

Abstract

Ranitidine (RAN) is a drug from the histamine H2 receptor antagonist class and is used to prevent excessive production of stomach acid. An electrochemical investigation of the RAN in pharmaceutical preparation and spiked human urine was performed for the using a boron-doped diamond electrode (BDDE). Voltammetric measurements were performed in a pH 11 BR solution supplemented with the anionic surfactant, sodium dodecyl sulfate (SDS). In the proposed method using optimized experimental conditions, linearity was obtained for RAN in the concentration range of 0.8-50.0 μM. The LOD value obtained is 0.22 μM. Good selectivity, accuracy, precision, and acceptable repeatability were also achieved in this proposed electrochemical sensor. Finally, this electrochemical sensor was successfully used for RAN detection in pharmaceutical samples.

Keywords

References

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Details

Primary Language

English

Subjects

Electroanalytical Chemistry , Analytical Chemistry (Other)

Journal Section

Research Article

Authors

Hasret Subak
0000-0003-0100-2529
Türkiye

Pınar Talay Pınar ^*
0000-0003-1027-1456
Türkiye

Publication Date

June 30, 2024

Submission Date

January 21, 2024

Acceptance Date

April 6, 2024

Published in Issue

Year 2024 Volume: 45 Number: 2

DOI

https://doi.org/10.17776/csj.1423273

IZ

https://izlik.org/JA48ST96EF

Cite

RIS / Bibtex

APA

Subak, H., & Talay Pınar, P. (2024). Electrochemical Oxidation of Ranitidine using a Boron-Doped Diamond Electrode in the Presence of Anionic Surfactant: A Comprehensive Investigation. Cumhuriyet Science Journal, 45(2), 249-255. https://doi.org/10.17776/csj.1423273

Cited By

A review of pretreatment and analytical methods for H2 receptor antagonists: An update since 2019

Journal of Chromatography A

https://doi.org/10.1016/j.chroma.2025.466564

Electrochemical Oxidation of Ranitidine using a Boron-Doped Diamond Electrode in the Presence of Anionic Surfactant: A Comprehensive Investigation

Abstract

Keywords

Öz

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

A review of pretreatment and analytical methods for H2 receptor antagonists: An update since 2019