The Strain-Dependent Antimicrobial and Antibiofilm effect of Cis and Trans-Vaccenic Acid against Pseudomonas Aeruginosa

Ayşenur Yazıcı

doi:10.17776/csj.1341700

EN

The Strain-Dependent Antimicrobial and Antibiofilm effect of Cis and Trans-Vaccenic Acid against Pseudomonas Aeruginosa

Abstract

This study, it was aimed to investigate the antibacterial and antibiofilm activity of cis and trans-vaccenic acid against Pseudomonas aeruginosa. In the study, four different P. aeruginosa strains were used. Antibacterial activity was determined by microdilution and growth curve. The antibiofilm activity was determined by crystal violet assay. In addition, the effect of vaccenic acids on pyocyanin production was investigated. The minimum inhibitory concentration (MIC) of cis and trans-vaccenic acid against all strains was determined as 128-256 μg/mL, and the minimum biofilm inhibitory concentration (MBIC) value was 8-512 μg/mL. While vaccenic acids reduced cell growth in three strains, they also significantly inhibited pyocyanin production. In one strain, it inhibited biofilm formation without affecting cell growth. As a result, the presence of antibacterial and antibiofilm activity of cis and trans-vaccenic acid against P. aeruginosa was determined as potential agents in the fight against this bacteria.

Keywords

References

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Details

Primary Language

English

Subjects

Biochemistry and Cell Biology (Other)

Journal Section

Research Article

Authors

Ayşenur Yazıcı ^*
0000-0002-3369-6791
Türkiye

Publication Date

March 28, 2024

Submission Date

August 11, 2023

Acceptance Date

January 31, 2024

Published in Issue

Year 2024 Volume: 45 Number: 1

DOI

https://doi.org/10.17776/csj.1341700

IZ

https://izlik.org/JA93AB77PY

Cite

RIS / Bibtex

APA

Yazıcı, A. (2024). The Strain-Dependent Antimicrobial and Antibiofilm effect of Cis and Trans-Vaccenic Acid against Pseudomonas Aeruginosa. Cumhuriyet Science Journal, 45(1), 1-7. https://doi.org/10.17776/csj.1341700

Cited By

Phytochemical Screening, FT-IR and GC-MS Analysis of Extracts from Aloe Aculeata Pole-Evans Leaves used for Managing Poultry Health in Drylands of Zimbabwe

Journal of Phytochemical Insights

https://doi.org/10.71193/jpci.20250012

Fatty Acids as Prebiotics and Their Role in Antibiofilm Activity

Antibiotics

https://doi.org/10.3390/antibiotics15010057

The Strain-Dependent Antimicrobial and Antibiofilm effect of Cis and Trans-Vaccenic Acid against Pseudomonas Aeruginosa

Abstract

Keywords

Öz

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Phytochemical Screening, FT-IR and GC-MS Analysis of Extracts from Aloe Aculeata Pole-Evans Leaves used for Managing Poultry Health in Drylands of Zimbabwe

Fatty Acids as Prebiotics and Their Role in Antibiofilm Activity