Green Synthesis of Gold Nanoparticles Using Aqueous Extract of Asphodelus Aestivus, Coating with Chitosan Biopolymer and Cytotoxicity Studies

Ersen Yılmaz; Mehmet Ateş; Muhammed Erbay

doi:10.17776/csj.1077429

EN

Green Synthesis of Gold Nanoparticles Using Aqueous Extract of Asphodelus Aestivus, Coating with Chitosan Biopolymer and Cytotoxicity Studies

Abstract

The green synthesis of gold nanoparticles (Au-NPs) was carried out by pouring the aqueous extract of East Anatolian origin Asphodelus aestivus plant onto aqueous gold metal ions and reducing them via single-step one- pot method. The absorption peak of the synthesized nanoparticles gave a maximum at 575 nm. All the X-ray diffraction peaks at 2θ = 38.25 , 44.46 , 64.64 and 77.20 that index to (111), (200), (220), and (311) planes verify the successful synthesis of Au-NPs. Mostly spherical shape particles showed a homogeneous distribution with size range 20±5 nm are measured using TEM. From the FTIR spectrum, the peaks are seems to be related to phenolic compounds, flavonoids, benzophenones, terpenoids and anthocyanins which assume that they could act as the reducing agents. The plant extraction, one-pot, single-step method used is environmentally safe without the role of synthetic materials which is highly potential in mild and green synthesis applications. The Au-NPs were coated with chitosan biopolymer in aquatic solution medium and verified by SEM. Then, cytotoxic investigations of the biosynthesized Au-NPs were carried out by HUVEC cells. Au-NPs were showed toxic effects on cell culture, even if in a small amount. However, chitosan biopolymer coating increased cell viability.

Keywords: Gold nanoparticle, Biosynthesis, Asphodelus aestivus, Biopolymer coating, Cytotoxicity

Keywords

Supporting Institution

Munzur Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimi (MUNIBAP)

Project Number

YLMUB019-03

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Ersen Yılmaz ^*
0000-0002-8567-1668
Türkiye

Mehmet Ateş
0000-0002-2764-6579
Türkiye

Muhammed Erbay
0000-0003-2335-1009
Türkiye

Publication Date

September 30, 2022

Submission Date

February 23, 2022

Acceptance Date

June 9, 2022

Published in Issue

Year 2022 Volume: 43 Number: 3

DOI

https://doi.org/10.17776/csj.1077429

IZ

https://izlik.org/JA82RS59JD

Cite

RIS / Bibtex

APA

Yılmaz, E., Ateş, M., & Erbay, M. (2022). Green Synthesis of Gold Nanoparticles Using Aqueous Extract of Asphodelus Aestivus, Coating with Chitosan Biopolymer and Cytotoxicity Studies. Cumhuriyet Science Journal, 43(3), 416-422. https://doi.org/10.17776/csj.1077429

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Microbial Pathogenesis

https://doi.org/10.1016/j.micpath.2025.108148

Öz

Green Synthesis of Gold Nanoparticles Using Aqueous Extract of Asphodelus Aestivus, Coating with Chitosan Biopolymer and Cytotoxicity Studies

Abstract

Keywords

Supporting Institution

Project Number

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Photothermal and radiotherapy with alginate-coated gold nanoparticles for breast cancer treatment

Antibacterial profiling of selenium nanoparticles synthesized from Crinum species