In this study, oleic acid-PVA based amphiphilic polymer micelles were prepared for vitamin D encapsulation. The amphiphilic polymer encapsulations were characterized using Fourier transformed infrared spectroscopy (FTIR) and nuclear magnetic resonance spectroscopy (1H-NMR). The goal of the study was to create micelles by using a lipophilic and biocompatible polymer. An oleic acid-substituted polyvinyl alcohol polymer was created through an acidic esterification reaction. The chemical structure of the polymer was disclosed by FTIR. To calculate the polymer's substitution ratio, 1H-NMR was used. Micellization was used to encapsulate vitamin D. Scanning electron microscope (SEM) analysis was used to determine the crucial micelle concentration and the size of the oleic acid-modified PVA. Ultraviolet–visible (UV) spectroscopy was used to analyze the release of vitamin D at various pH levels. As a result, vitamin D can be enclosed in PVA polymer that has been substituted with oleic acid.
Birincil Dil | İngilizce |
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Konular | Polimer Bilimi ve Teknolojileri |
Bölüm | ARAŞTIRMA MAKALELERİ |
Yazarlar | |
Yayımlanma Tarihi | 11 Kasım 2023 |
Gönderilme Tarihi | 20 Haziran 2023 |
Kabul Tarihi | 21 Ağustos 2023 |
Yayımlandığı Sayı | Yıl 2023 Cilt: 10 Sayı: 4 |