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Comparison of Characteristics and Antimicrobial Activity of Synthesized Zinc Oxide And Magnetite Iron Oxide Nanoparticles Using Four Different Plant Extracts

Yıl 2024, Cilt: 45 Sayı: 1, 20 - 28, 28.03.2024

Burcu Aydoğdu Mehmet Aytar İlkay Ünal

https://doi.org/10.17776/csj.1370606

Öz

The aim of this study was to synthesize Zinc oxide (ZnO) and magnetite ıron oxide (Fe3O4) nanoparticles utilizing a precipitation method, employing plant extracts from Ocimum basilica(1), Cinnamomum zeylanicum(2), Lactarius salmonicolor(3) and Paeonia kesrouanensis(4) as reduction and stabilizing agents. Additionally, the antimicrobial activity of these nanoparticles against both gram-positive (S. aureus, ATCC 25923) and gram-negative (E. coli, ATCC 25922; P. aeroginosa, PAO1), bacteria as well as fungus (C. albicans 90028) was evaluated. The nanoparticles (NPs) were characterised by various analyses, including TEM, SEM, XRD, FTIR, DSL, and zeta potential. Based on the TEM image, the ZnONPs exhibited a cluster of flower-like structures, whereas the Fe3O4NPs displayed a spherical shape with a varying size distribution. The zeta potential values for ZnO NPs ranged from -5.35 to -16.9, while for Fe3O4NPs ranged from -7.43 to -20.7. All ZnO nanoparticles exhibited antimicrobial activity exclusively against the S. aureus strain, whereas Fe3O4NPs did not demonstrate any antibacterial effect.

Anahtar Kelimeler

Antimictobial activity Green synthesis Magnetite iron oxide Zinc oxide

Kaynakça

  • [1] N. Joudeh and D. Linke, Nanoparticle classification, physicochemical properties, characterization, and applications: a comprehensive review for biologists, J Nanobiotechnology 20 (1) (2022) 1–29.
  • [2] Yusuf et al., Nanoparticles as Drug Delivery Systems: A Review of the Implication of Nanoparticles’ Physicochemical Properties on Responses in Biological Systems, Polymers (Basel) 15 (7) (2023).
  • [3] Khan, K. Saeed, and I. Khan, Nanoparticles: Properties, applications and toxicities, Arabian Journal of Chemistry 12 (7) (2019) 908–931.
  • [4] J. Ali et al., Green synthesized zinc oxide nanostructures and their applications in dye-sensitized solar cells and photocatalysis: A review, Mater Today Commun 36 (August) (2023) 106840.
  • [5] J.R. Vargas-Ortiz, C. Gonzalez, and K. Esquivel, Magnetic Iron Nanoparticles: Synthesis, Surface Enhancements, and Biological Challenges, Processes 10 (11) (2022).
  • [6] H. Chopra et al., Green Metallic Nanoparticles: Biosynthesis to Applications, Front Bioeng Biotechnol 10 (April) (2022) 1–29.
  • [7] Alayli et al., Synthesis of Nanoparticles by Green Synthesis Method, International Journal of Innovative Research and Reviews 1 (1) (2017) 6–9.
  • [8] Chaudhary et al., Antimicrobial activity of zinc oxide nanoparticles synthesized from Aloe vera peel extract, SN Appl Sci 1 (1) (2019) 1–9.
  • [9] M.F. Sohail et al., Green synthesis of zinc oxide nanoparticles by Neem extract as multi-facet therapeutic agents, J Drug Deliv Sci Technol 59 (June) (2020) 101911.
  • [10] G.A. Naikoo et al., Bioinspired and green synthesis of nanoparticles from plant extracts with antiviral and antimicrobial properties: A critical review, Journal of Saudi Chemical Society 25 (9) (2021) 101304.
  • [11] I.K. Siakavella et al., Effect of plant extracts on the characteristics of silver nanoparticles for topical application, Pharmaceutics 12 (12) (2020) 1–17.
  • [12] P.D. Twilley, S. Rademan, and N. Lall, Are medicinal plants effective for skin cancer?, in Medicinal Plants for Holistic Health and Well-Being, Elsevier, (2017): pp. 13–75.
  • [13] B. Feng et al., Basil polysaccharide inhibits hypoxia-induced hepatocellular carcinoma metastasis and progression through suppression of HIF-1α-mediated epithelial-mesenchymal transition, Int J Biol Macromol 137 (2019) 32–44.
  • [14] I. Rahayu, Casey Christiany, and Susana Elya Sudrajat, The Potency of Cinnamomum Zeylanicum to Prevent Diseases: a Review, Eureka Herba Indonesia 2 (1) (2021) 52–62.
  • [15] Z. Wang et al., Origins, phytochemistry, pharmacology, analytical methods and safety of cortex moutan (paeonia suffruticosa Andrew): A systematic review, Molecules 22 (6) (2017).
  • [16] A. Ozdemir, Antıoxıdant Capacıty And Antımıcrobıal Actıvıty of Paeonıa Peregrına L [Usak-Itecık Tulıp] Extracts and Its Phenolıc and Flavonoıd Compounds, The Ulutas Medıcal Journal 5 (4) (2019) 1.
  • [17] G. Athanasakis et al., Antioxidant properties of the wild edible mushroom lactarius salmonicolor, J Med Food 16 (8) (2013) 760–764.
  • [18] B.O. Asimeng et al., Characterization and Inhibitory Effects of Magnetic Iron Oxide Nanoparticles Synthesized from Plant Extracts on HeLa Cells, Int J Biomater 2020 (2020) 15–18.
  • [19] P. Sharma et al., Application of ZnO-based nanocomposites for vaccines and cancer immunotherapy, Pharmaceutics 11 (10) (2019) 6–10.
  • [20] A. Naveed Ul Haq et al., Synthesis Approaches of Zinc Oxide Nanoparticles: The Dilemma of Ecotoxicity, J Nanomater 2017 (Table 1) (2017).
  • [21] G.T. Mazitova et al., Synthesis and Properties of Zinc Oxide Nanoparticles: Advances and Prospects, Rev J Chem 9 (2) (2019) 127–152.
  • [22] K. Parajuli, A.K. Sah, and H. Paudyal, Green Synthesis of Magnetite Nanoparticles Using Aqueous Leaves Extracts of <i>Azadirachta indica</i> and Its Application for the Removal of As(V) from Water, Green and Sustainable Chemistry 10 (04) (2020) 117–132.
  • [23] K. Handore et al., Novel green route of synthesis of ZnO nanoparticles by using natural biodegradable polymer and its application as a catalyst for oxidation of aldehydes, Journal of Macromolecular Science, Part A: Pure and Applied Chemistry 51 (12) (2014) 941–947.
  • [24] R. Gomathi, H. Suhana, and D. Paradesi, Characterization Study of Cytotoxicity of Green Synthesized ZnO Nanoparticles Loaded with Anti-Cancer Doxorubicin Drug, ChemistrySelect 6 (18) (2021) 4533–4538.
  • [25] M.B. Nayan et al., Comparative Study on the Effects of Surface Area, Conduction Band and Valence Band Positions on the Photocatalytic Activity of ZnO-M<sub>x</sub>O<sub>y</sub> Heterostructures, J Water Resour Prot 11 (03) (2019) 357–370.
  • [26] F. Ahangaran, A. Hassanzadeh, and S. Nouri, Surface modification of Fe3O4@SiO2 microsphere by silane coupling agent, Int Nano Lett 3 (1) (2013).
  • [27] C.M. Hoo et al., A comparison of atomic force microscopy (AFM) and dynamic light scattering (DLS) methods to characterize nanoparticle size distributions, Journal of Nanoparticle Research 10 (SUPPL. 1) (2008) 89–96.
  • [28] M. Danaei et al., Impact of particle size and polydispersity index on the clinical applications of lipidic nanocarrier systems, Pharmaceutics 10 (2) (2018) 1–17.
  • [29] R. Xu, Progress in nanoparticles characterization: Sizing and zeta potential measurement, Particuology 6 (2) (2008) 112–115.
  • [30] S.C. Endres, L.C. Ciacchi, and L. Mädler, A review of contact force models between nanoparticles in agglomerates, aggregates, and films, J Aerosol Sci 153 (November 2020) (2021).
  • [31] S. Saqib et al., Synthesis, characterization and use of iron oxide nano particles for antibacterial activity, Microsc Res Tech 82 (4) (2019) 415–420.

Yıl 2024, Cilt: 45 Sayı: 1, 20 - 28, 28.03.2024

Burcu Aydoğdu Mehmet Aytar İlkay Ünal

https://doi.org/10.17776/csj.1370606

Öz

Kaynakça

  • [1] N. Joudeh and D. Linke, Nanoparticle classification, physicochemical properties, characterization, and applications: a comprehensive review for biologists, J Nanobiotechnology 20 (1) (2022) 1–29.
  • [2] Yusuf et al., Nanoparticles as Drug Delivery Systems: A Review of the Implication of Nanoparticles’ Physicochemical Properties on Responses in Biological Systems, Polymers (Basel) 15 (7) (2023).
  • [3] Khan, K. Saeed, and I. Khan, Nanoparticles: Properties, applications and toxicities, Arabian Journal of Chemistry 12 (7) (2019) 908–931.
  • [4] J. Ali et al., Green synthesized zinc oxide nanostructures and their applications in dye-sensitized solar cells and photocatalysis: A review, Mater Today Commun 36 (August) (2023) 106840.
  • [5] J.R. Vargas-Ortiz, C. Gonzalez, and K. Esquivel, Magnetic Iron Nanoparticles: Synthesis, Surface Enhancements, and Biological Challenges, Processes 10 (11) (2022).
  • [6] H. Chopra et al., Green Metallic Nanoparticles: Biosynthesis to Applications, Front Bioeng Biotechnol 10 (April) (2022) 1–29.
  • [7] Alayli et al., Synthesis of Nanoparticles by Green Synthesis Method, International Journal of Innovative Research and Reviews 1 (1) (2017) 6–9.
  • [8] Chaudhary et al., Antimicrobial activity of zinc oxide nanoparticles synthesized from Aloe vera peel extract, SN Appl Sci 1 (1) (2019) 1–9.
  • [9] M.F. Sohail et al., Green synthesis of zinc oxide nanoparticles by Neem extract as multi-facet therapeutic agents, J Drug Deliv Sci Technol 59 (June) (2020) 101911.
  • [10] G.A. Naikoo et al., Bioinspired and green synthesis of nanoparticles from plant extracts with antiviral and antimicrobial properties: A critical review, Journal of Saudi Chemical Society 25 (9) (2021) 101304.
  • [11] I.K. Siakavella et al., Effect of plant extracts on the characteristics of silver nanoparticles for topical application, Pharmaceutics 12 (12) (2020) 1–17.
  • [12] P.D. Twilley, S. Rademan, and N. Lall, Are medicinal plants effective for skin cancer?, in Medicinal Plants for Holistic Health and Well-Being, Elsevier, (2017): pp. 13–75.
  • [13] B. Feng et al., Basil polysaccharide inhibits hypoxia-induced hepatocellular carcinoma metastasis and progression through suppression of HIF-1α-mediated epithelial-mesenchymal transition, Int J Biol Macromol 137 (2019) 32–44.
  • [14] I. Rahayu, Casey Christiany, and Susana Elya Sudrajat, The Potency of Cinnamomum Zeylanicum to Prevent Diseases: a Review, Eureka Herba Indonesia 2 (1) (2021) 52–62.
  • [15] Z. Wang et al., Origins, phytochemistry, pharmacology, analytical methods and safety of cortex moutan (paeonia suffruticosa Andrew): A systematic review, Molecules 22 (6) (2017).
  • [16] A. Ozdemir, Antıoxıdant Capacıty And Antımıcrobıal Actıvıty of Paeonıa Peregrına L [Usak-Itecık Tulıp] Extracts and Its Phenolıc and Flavonoıd Compounds, The Ulutas Medıcal Journal 5 (4) (2019) 1.
  • [17] G. Athanasakis et al., Antioxidant properties of the wild edible mushroom lactarius salmonicolor, J Med Food 16 (8) (2013) 760–764.
  • [18] B.O. Asimeng et al., Characterization and Inhibitory Effects of Magnetic Iron Oxide Nanoparticles Synthesized from Plant Extracts on HeLa Cells, Int J Biomater 2020 (2020) 15–18.
  • [19] P. Sharma et al., Application of ZnO-based nanocomposites for vaccines and cancer immunotherapy, Pharmaceutics 11 (10) (2019) 6–10.
  • [20] A. Naveed Ul Haq et al., Synthesis Approaches of Zinc Oxide Nanoparticles: The Dilemma of Ecotoxicity, J Nanomater 2017 (Table 1) (2017).
  • [21] G.T. Mazitova et al., Synthesis and Properties of Zinc Oxide Nanoparticles: Advances and Prospects, Rev J Chem 9 (2) (2019) 127–152.
  • [22] K. Parajuli, A.K. Sah, and H. Paudyal, Green Synthesis of Magnetite Nanoparticles Using Aqueous Leaves Extracts of <i>Azadirachta indica</i> and Its Application for the Removal of As(V) from Water, Green and Sustainable Chemistry 10 (04) (2020) 117–132.
  • [23] K. Handore et al., Novel green route of synthesis of ZnO nanoparticles by using natural biodegradable polymer and its application as a catalyst for oxidation of aldehydes, Journal of Macromolecular Science, Part A: Pure and Applied Chemistry 51 (12) (2014) 941–947.
  • [24] R. Gomathi, H. Suhana, and D. Paradesi, Characterization Study of Cytotoxicity of Green Synthesized ZnO Nanoparticles Loaded with Anti-Cancer Doxorubicin Drug, ChemistrySelect 6 (18) (2021) 4533–4538.
  • [25] M.B. Nayan et al., Comparative Study on the Effects of Surface Area, Conduction Band and Valence Band Positions on the Photocatalytic Activity of ZnO-M<sub>x</sub>O<sub>y</sub> Heterostructures, J Water Resour Prot 11 (03) (2019) 357–370.
  • [26] F. Ahangaran, A. Hassanzadeh, and S. Nouri, Surface modification of Fe3O4@SiO2 microsphere by silane coupling agent, Int Nano Lett 3 (1) (2013).
  • [27] C.M. Hoo et al., A comparison of atomic force microscopy (AFM) and dynamic light scattering (DLS) methods to characterize nanoparticle size distributions, Journal of Nanoparticle Research 10 (SUPPL. 1) (2008) 89–96.
  • [28] M. Danaei et al., Impact of particle size and polydispersity index on the clinical applications of lipidic nanocarrier systems, Pharmaceutics 10 (2) (2018) 1–17.
  • [29] R. Xu, Progress in nanoparticles characterization: Sizing and zeta potential measurement, Particuology 6 (2) (2008) 112–115.
  • [30] S.C. Endres, L.C. Ciacchi, and L. Mädler, A review of contact force models between nanoparticles in agglomerates, aggregates, and films, J Aerosol Sci 153 (November 2020) (2021).
  • [31] S. Saqib et al., Synthesis, characterization and use of iron oxide nano particles for antibacterial activity, Microsc Res Tech 82 (4) (2019) 415–420.
Toplam 31 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Biyomateryaller
Bölüm Natural Sciences
Yazarlar

Burcu Aydoğdu 0000-0002-3309-1995

Mehmet Aytar 0000-0002-8083-7358

İlkay Ünal 0000-0002-1587-4187

Yayımlanma Tarihi 28 Mart 2024
Gönderilme Tarihi 3 Ekim 2023
Kabul Tarihi 12 Ocak 2024
Yayımlandığı Sayı Yıl 2024Cilt: 45 Sayı: 1

Kaynak Göster

APA Aydoğdu, B., Aytar, M., & Ünal, İ. (2024). Comparison of Characteristics and Antimicrobial Activity of Synthesized Zinc Oxide And Magnetite Iron Oxide Nanoparticles Using Four Different Plant Extracts. Cumhuriyet Science Journal, 45(1), 20-28. https://doi.org/10.17776/csj.1370606
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