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Fungal Biotransformation of Cedryl Formate

Yıl 2023, Cilt: 51 Sayı: 3, 283 - 287, 16.07.2023
https://doi.org/10.15671/hjbc.1244894

Öz

Cedryl formate is a synthetic fragrance compound, which is an ester derivative of the sesquiterpenoid cedrol, found in different parts of the cedar tree/cedarwood with a characteristic fragrance. Cedryl formate is used in cosmetics and personal care products like fragrances, perfumes, as well as in the chemical and agriculture industries in various forms. In the present work, the microbial transformation of the formate was evaluated by 13 fungal cultures to produce new derivatives. Among the evaluated, the plant pathogenic fungus Aspergillus niger NRRL 326, biotransformed to the metabolite 8-cedren-3β-ol derivative with 6.2% yield. The structure of the chromatographically purified metabolite was elucidated by NMR and spectroscopic methods.

Destekleyen Kurum

Scientific and Technological Research Council of Turkey

Proje Numarası

Grant no: 00530.STZ.2010-1

Teşekkür

The authors would like to thank to the Turkish Ministry of Science, Industry and Technology (Grant no: 00530.STZ.2010-1) for partial financial support. The authors would like to dedicate this work for the 75th birthday of Prof. Dr. Yoshiaki NOMA a master of biotransformations.

Kaynakça

  • M.A. Longo, M.A. Sanroman, Production of food aroma compounds: microbial and enzymatic methodologies, Food Technol. Biotechnol., 44 (2006) 335-353.
  • R. Rowe, Chemistry and technology of flavours and fragrances. Blackwell Publishing, Oxford, 2005.
  • J.P. Horst Surburg, Common Fragrance and Flavor Materials: Preparation, Properties and Uses. Individual Fragrance and Flavor Materials. Wiley‐VCH Verlag GmbH & Co. KGaA, 2009.
  • P. Kraft, Perspectives in Flavor and Fragrance Research. The Search for New Fragrance Ingredients for Functional Perfumery, 2005.
  • J. Scognamiglio, C.S. Letizia, A.M. Api, Fragrance material review on 1-(3,3-dimethylcyclohexyl)ethan-1-one. Food Chem. Toxicol.,62 (2013) 56-60.
  • R. G. Berger, Flavours and Fragrances Chemistry, Bioprocessing and Sustainability, Springer, 2007.
  • Z. Jiang, C. Kempinski, J. Chappell, Extraction and Analysis of Terpenes/Terpenoids. Curr. Protoc. Plant Biol., 1 (2016) 345-358.
  • G. Riezebos, J. H. Greaves, The Determination of Cedrol, and the Total Alcohol Content of Oils of Cedarwood, by Formylation, Analyst, 94 (1969) 148-151.
  • M. Garriga, A. P. Thurow, T. Thurow, R. Conner, D. Brandenberger, Commercial value of juniper on the Edwards Plateau, Texas Agricultural Experiment Station Technical Report, San Angelo, Texas, USA, 1997.
  • Ö. Özşen Batur, İ. Kiran, F. Demirci, K.H.C. Başer, Fungal biotransformation of cedramber, Biocatal. Biotransformation, 40 (2021) 248-251.
  • İ. Kiran, K.H.C. Başer, F. Demirci, Ö. Özşen Batur, Microbial biotransformation 3,3-Dimethylcyclohexyl methyl ketone and Antimicrobial Evaluation, Hacettepe J. Biol. Chem., 50(3) (2022) 263-267.

Sedril Formatın Mikrobiyal Dönüşümü

Yıl 2023, Cilt: 51 Sayı: 3, 283 - 287, 16.07.2023
https://doi.org/10.15671/hjbc.1244894

Öz

Sedril format sedrol molekülünün sentetik esteri olan bir koku bileşiğidir. Sedrol sedir ağacının uçucu yağı dahil farklı bulunan bir seskiterpen aromatik bileşiktir. Sedirin karakteristik kokusunu vermektedir. Sedril format, parfüm ve kozmetik gibi kişisel bakım ürünleri ile kimya, ve hatta tarım endüstrisi gibi alanlarda kullanılmaktadır. Bu çalışmada format substratı farklı 13 fungal kültür ile türevlendirilmesi incelenmiştir. Sonuçlar arasında, bitki patojeni olan Aspergillus niger NRRL 326, substratı %6.2 verimle 8-cedren-3β-ol metabolitine biyolojik olarak ilk defa dönüştürülmüştür. Kromatografik yöntemlerle saflaştırılan metabolitin yapısı NMR ve spektroskopik metodlar kullanılarak aydınlatılmıştır.

Proje Numarası

Grant no: 00530.STZ.2010-1

Kaynakça

  • M.A. Longo, M.A. Sanroman, Production of food aroma compounds: microbial and enzymatic methodologies, Food Technol. Biotechnol., 44 (2006) 335-353.
  • R. Rowe, Chemistry and technology of flavours and fragrances. Blackwell Publishing, Oxford, 2005.
  • J.P. Horst Surburg, Common Fragrance and Flavor Materials: Preparation, Properties and Uses. Individual Fragrance and Flavor Materials. Wiley‐VCH Verlag GmbH & Co. KGaA, 2009.
  • P. Kraft, Perspectives in Flavor and Fragrance Research. The Search for New Fragrance Ingredients for Functional Perfumery, 2005.
  • J. Scognamiglio, C.S. Letizia, A.M. Api, Fragrance material review on 1-(3,3-dimethylcyclohexyl)ethan-1-one. Food Chem. Toxicol.,62 (2013) 56-60.
  • R. G. Berger, Flavours and Fragrances Chemistry, Bioprocessing and Sustainability, Springer, 2007.
  • Z. Jiang, C. Kempinski, J. Chappell, Extraction and Analysis of Terpenes/Terpenoids. Curr. Protoc. Plant Biol., 1 (2016) 345-358.
  • G. Riezebos, J. H. Greaves, The Determination of Cedrol, and the Total Alcohol Content of Oils of Cedarwood, by Formylation, Analyst, 94 (1969) 148-151.
  • M. Garriga, A. P. Thurow, T. Thurow, R. Conner, D. Brandenberger, Commercial value of juniper on the Edwards Plateau, Texas Agricultural Experiment Station Technical Report, San Angelo, Texas, USA, 1997.
  • Ö. Özşen Batur, İ. Kiran, F. Demirci, K.H.C. Başer, Fungal biotransformation of cedramber, Biocatal. Biotransformation, 40 (2021) 248-251.
  • İ. Kiran, K.H.C. Başer, F. Demirci, Ö. Özşen Batur, Microbial biotransformation 3,3-Dimethylcyclohexyl methyl ketone and Antimicrobial Evaluation, Hacettepe J. Biol. Chem., 50(3) (2022) 263-267.
Toplam 11 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Mühendislik
Bölüm Articles
Yazarlar

Özge Özşen Batur 0000-0002-6908-1174

İsmail Kıran 0000-0003-4929-9341

Kemal Hüsnü Can Başer 0000-0003-2710-0231

Fatih Demirci 0000-0003-1497-3017

Proje Numarası Grant no: 00530.STZ.2010-1
Erken Görünüm Tarihi 14 Temmuz 2023
Yayımlanma Tarihi 16 Temmuz 2023
Kabul Tarihi 17 Nisan 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 51 Sayı: 3

Kaynak Göster

APA Özşen Batur, Ö., Kıran, İ., Başer, K. H. C., Demirci, F. (2023). Fungal Biotransformation of Cedryl Formate. Hacettepe Journal of Biology and Chemistry, 51(3), 283-287. https://doi.org/10.15671/hjbc.1244894
AMA Özşen Batur Ö, Kıran İ, Başer KHC, Demirci F. Fungal Biotransformation of Cedryl Formate. HJBC. Temmuz 2023;51(3):283-287. doi:10.15671/hjbc.1244894
Chicago Özşen Batur, Özge, İsmail Kıran, Kemal Hüsnü Can Başer, ve Fatih Demirci. “Fungal Biotransformation of Cedryl Formate”. Hacettepe Journal of Biology and Chemistry 51, sy. 3 (Temmuz 2023): 283-87. https://doi.org/10.15671/hjbc.1244894.
EndNote Özşen Batur Ö, Kıran İ, Başer KHC, Demirci F (01 Temmuz 2023) Fungal Biotransformation of Cedryl Formate. Hacettepe Journal of Biology and Chemistry 51 3 283–287.
IEEE Ö. Özşen Batur, İ. Kıran, K. H. C. Başer, ve F. Demirci, “Fungal Biotransformation of Cedryl Formate”, HJBC, c. 51, sy. 3, ss. 283–287, 2023, doi: 10.15671/hjbc.1244894.
ISNAD Özşen Batur, Özge vd. “Fungal Biotransformation of Cedryl Formate”. Hacettepe Journal of Biology and Chemistry 51/3 (Temmuz 2023), 283-287. https://doi.org/10.15671/hjbc.1244894.
JAMA Özşen Batur Ö, Kıran İ, Başer KHC, Demirci F. Fungal Biotransformation of Cedryl Formate. HJBC. 2023;51:283–287.
MLA Özşen Batur, Özge vd. “Fungal Biotransformation of Cedryl Formate”. Hacettepe Journal of Biology and Chemistry, c. 51, sy. 3, 2023, ss. 283-7, doi:10.15671/hjbc.1244894.
Vancouver Özşen Batur Ö, Kıran İ, Başer KHC, Demirci F. Fungal Biotransformation of Cedryl Formate. HJBC. 2023;51(3):283-7.

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