A new spectrophotometric study with ortho hydroxy schiff base for the determination of aluminum in drug

Tufan Güray; Dila Ercengiz; Ülkü Dilek Uysal

doi:10.17776/csj.693029

Research Article

A new spectrophotometric study with ortho hydroxy schiff base for the determination of aluminum in drug

Year 2020, , 456 - 461, 25.06.2020

Tufan Güray , Dila Ercengiz Ülkü Dilek Uysal

https://doi.org/10.17776/csj.693029

Abstract

In this study, a Schiff base called (E)-2-((2- hydroxy -3- methoxy benzylidene)amino)-5- methylphenol (L) was used as a ligand. Spectrophotometric properties of the ligand have been defined and the optimum conditions for determining aluminium by complex by UV-Vis. spectrophotometry. The absorbance of Al(III)-L complex obeys Beer’s law between 1.4 µg mL–1 and 13.5 µg mL–1 for the aluminium in the optimum conditions. Under optimum conditions, the determination of aluminium in Kompensan® drug was done successfully. The LOD and LOQ values of the developed method were 0.01139 μg mL-1 and 0.0345 μg mL-1, respectively for the ligand.

Keywords

Aluminium, Schiff base, UV- Vis. spectrophotometry, Kompensan®

Supporting Institution

Anadolu Üniversitesi

Project Number

1509F633

Thanks

We kindly acknowledge to Anadolu University Scientific Research Projects (No:1509F633) for its support to this study.

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