Ranitidine (RAN) is a drug from the histamine H2 receptor antagonist class and is used to prevent excessive production of stomach acid. An electrochemical investigation of the RAN in pharmaceutical preparation and spiked human urine was performed for the using a boron-doped diamond electrode (BDDE). Voltammetric measurements were performed in a pH 11 BR solution supplemented with the anionic surfactant, sodium dodecyl sulfate (SDS). In the proposed method using optimized experimental conditions, linearity was obtained for RAN in the concentration range of 0.8-50.0 μM. The LOD value obtained is 0.22 μM. Good selectivity, accuracy, precision, and acceptable repeatability were also achieved in this proposed electrochemical sensor. Finally, this electrochemical sensor was successfully used for RAN detection in pharmaceutical samples.
Ranitidine Electrochemical detection Boron-doped diamond electrode Surfactant Pharmaceutical samples
Birincil Dil | İngilizce |
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Konular | Elektroanalitik Kimya, Analitik Kimya (Diğer) |
Bölüm | Natural Sciences |
Yazarlar | |
Yayımlanma Tarihi | 30 Haziran 2024 |
Gönderilme Tarihi | 21 Ocak 2024 |
Kabul Tarihi | 6 Nisan 2024 |
Yayımlandığı Sayı | Yıl 2024 |