Research Article
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Year 2019, Volume: 4 Issue: 2, 46 - 59, 28.10.2019

Abstract

References

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Alliin mitigates Cecal Ligation Puncture (CLP)-induced lung injury through antioxidant and antiinflammatory effects

Year 2019, Volume: 4 Issue: 2, 46 - 59, 28.10.2019

Abstract

Purpose/Aim of the StudyThe purpose of this research is to examine protective effect of alliin in lung injury induced by cecal ligation and puncture. 

Materials and Methods:In this study, the rats were assigned to 4 groups and were planned as follows; sham control, CLP, CLP + 100 mg/kg alliin and CLP + 200 mg/kg alliin. Some oxidant, antioxidant and inflammatory parameters were evaluated in lung tissues obtained at the end of the experiment. 

Results: Results  proved that the oxidant and inflammatory biomarkers increased and antioxidant biomarkers decreased in the CLP group compared to sham control group but the antioxidant parameters increased and oxidant parameters decreased in treatment group compared to CLP group. 

Conclusion: Our results have demonstrated that the administration of alliin is an effective method against oxidative lung injury caused by cecal ligation puncture-sepsis model.

 

References

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  • 21. Helen A, Krishnakumar K, Vijayammal PL, et al. A comparative study of antioxidants S-allyl cysteine sulfoxide and vitamin E on the damages induced by nicotine in rats. Pharmacology. 2003 Mar;67(3):113-7. doi: 10.1159/000067796. PubMed PMID: 12571405; eng.
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There are 60 citations in total.

Details

Primary Language English
Journal Section Volume IV, Issue II, 2019
Authors

Ayhan Tanyeli 0000-0002-0095-0917

Derya Güzel 0000-0002-7618-5043

Publication Date October 28, 2019
Published in Issue Year 2019 Volume: 4 Issue: 2

Cite

APA Tanyeli, A., & Güzel, D. (2019). Alliin mitigates Cecal Ligation Puncture (CLP)-induced lung injury through antioxidant and antiinflammatory effects. Turkish Journal of Science, 4(2), 46-59.
AMA Tanyeli A, Güzel D. Alliin mitigates Cecal Ligation Puncture (CLP)-induced lung injury through antioxidant and antiinflammatory effects. TJOS. October 2019;4(2):46-59.
Chicago Tanyeli, Ayhan, and Derya Güzel. “Alliin Mitigates Cecal Ligation Puncture (CLP)-Induced Lung Injury through Antioxidant and Antiinflammatory Effects”. Turkish Journal of Science 4, no. 2 (October 2019): 46-59.
EndNote Tanyeli A, Güzel D (October 1, 2019) Alliin mitigates Cecal Ligation Puncture (CLP)-induced lung injury through antioxidant and antiinflammatory effects. Turkish Journal of Science 4 2 46–59.
IEEE A. Tanyeli and D. Güzel, “Alliin mitigates Cecal Ligation Puncture (CLP)-induced lung injury through antioxidant and antiinflammatory effects”, TJOS, vol. 4, no. 2, pp. 46–59, 2019.
ISNAD Tanyeli, Ayhan - Güzel, Derya. “Alliin Mitigates Cecal Ligation Puncture (CLP)-Induced Lung Injury through Antioxidant and Antiinflammatory Effects”. Turkish Journal of Science 4/2 (October 2019), 46-59.
JAMA Tanyeli A, Güzel D. Alliin mitigates Cecal Ligation Puncture (CLP)-induced lung injury through antioxidant and antiinflammatory effects. TJOS. 2019;4:46–59.
MLA Tanyeli, Ayhan and Derya Güzel. “Alliin Mitigates Cecal Ligation Puncture (CLP)-Induced Lung Injury through Antioxidant and Antiinflammatory Effects”. Turkish Journal of Science, vol. 4, no. 2, 2019, pp. 46-59.
Vancouver Tanyeli A, Güzel D. Alliin mitigates Cecal Ligation Puncture (CLP)-induced lung injury through antioxidant and antiinflammatory effects. TJOS. 2019;4(2):46-59.