Mushrooms have been consumed as foodstuffs since time very old. From a nutritional point of view; In addition to containing low calories, it has a rich content in essential amino acids, carbohydrates, fibers, important vitamins and minerals. Antioxidants are one of the most studied topics in recent years and can be defined as a whole of systems that neutralize toxic products that occur as a result of cell metabolism. Antioxidant activities of water extracts of Agrocybe praecox (Pers.) Fayod mushrooms were obtained according to total phenolics, total flavonoids, metal chelation and ABTS methods. It was observed that some compounds were found in the extracts used by the analyzes performed in this study and the mushroom had antioxidant properties. In this study, the total amount of phenol contained in A. praecox mushroom was detected to be 52.7 mg GAE/g. The amount of quercetin was found to be 1.46 mg QE/g, catechin 23.2 mg CA/g it was found to have total flavonoid properties. The IC50 of the metal chelating activity was calculated as 5.74 mg. The ABTS+ radical scavening activity was calculated as 12.5 mg.
Creating new products by using the compounds present and detected in the fungus or isolating the enzymes with high activity in them and making them more useful in vitro will be an important medical contribution. In addition, determination of its cytotoxic feature will pave the way for new studies in pharmaceutical and medical fields.
Tubitak
1919B011904373
We would like to thank Nuri AKTAN a graduate of Van Yüzüncü Yıl University Faculty of Science Department of Molecular Biology and Genetics 2019-2020 for her contributions to fungal extraction and experimentation. Our work is supported by TÜBİTAK with the project numbered 1919B011904373.
Mantarlar, çok eski zamanlardan beri gıda maddesi olarak tüketilmektedir. Beslenme açısından bakıldığında; Düşük kalori içermesinin yanı sıra esansiyel amino asitler, karbonhidratlar, lifler, önemli vitaminler ve mineraller açısından zengin içeriğe sahiptir. Antioksidanlar, son yıllarda en çok çalışılan konulardan biridir ve hücre metabolizmasının bir sonucu olarak ortaya çıkan toksik ürünleri nötralize eden bir sistem bütünü olarak tanımlanabilir. Agrocybe praecox (Pers.) Fayod mantarlarının su ekstraktlarının antioksidan aktiviteleri total fenolikler, total flavonoidler, metal şelasyon ve ABTS yöntemlerine göre elde edildi. Bu çalışmada yapılan analizlerde kullanılan ekstraktlarda bazı bileşiklerin bulunduğu ve mantarın antioksidan özelliklere sahip olduğu görülmüştür. Çalışmanın sonunda A. praecox mantarında bulunan toplam fenol miktarı 52.7 mg GAE/g olarak tespit edildi. Kuersetin miktarı 1.46 mg QE/g, kateşin 23.2 mg CA/g toplam flavonoid özelliklere sahip olduğu hesaplandı. Metal şelatlama aktivitesinin IC50'si 5.74 mg olarak belirlendi. ABTS+ radikal süpürme aktivitesi 12.5 mg olarak hesaplandı.
Mantardan tespit edilen bileşiklerin kullanılması ve yüksek aktiviteye sahip enzimlerin izole edilmesiyle elde edilebilecek yeni ürünler önemli bir tıbbi katkı olacaktır. Ek olarak, sitotoksik özelliğinin belirlenmesi farmasötik ve tıbbi alanlarda yeni çalışmaların önünü açacaktır.
1919B011904373
Primary Language | English |
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Journal Section | RESEARCH ARTICLE |
Authors | |
Project Number | 1919B011904373 |
Publication Date | April 28, 2022 |
Published in Issue | Year 2022 Volume: 13 Issue: 1 |
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