Case Report
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Newly Diagnosed Patient with Primary Biliary Cholangitis: Case Report

Year 2020, Volume: 17 Issue: 3, 492 - 494, 25.12.2020
https://doi.org/10.35440/hutfd.733455

Abstract

Primary biliary cholangitis (PBC) is a slowly progressive chronic cholestatic granulomatous liver disease of unknown etiology, mostly affected by middle-aged women, accompanied by damage to the small bile ducts. PBK can cause serious diseases such as portal hypertension or liver failure and then progress to cirrhosis. As in this case, it should not be forgotten that it may come with non-specific symptoms, detailed history and diagnosis should be confirmed with necessary laboratory tests in patients suspected.

References

  • Santiago P, Scheinberg AR, Levy C. Cholestatic liver diseases: new targets, new therapies. Therapeutic Advances in Gastroenterology. 2018;11(1):1-15.
  • .Gershwin ME, Mackay IR. The causes of primary biliary cirrhosis: convenient and in convenient truths. Hepatology. 2008;47(2):737-745.
  • Tkcv.org [homepage on the Internet]. Primer biliyer kolanjit (Primer-biliyer siroz) Türkiye-Azerbaycan Ortak Hepatoloji Kursu [updated 29 Eylül 2017; cited mart 2020] Available from: www.tkcv.org
  • Malik A, Kardashian AA, Zakharia K, Bowlus CL, Tabibian JH. Pre-ventative care in cholestatic liver disease: Pearls for the specialist and subspecialist. LiverResearch. 2019;3(2):118-127.
  • Corpechot C, Poupon R, Chazouilleres O. New treatments / targets for primary biliary cholangitis. JHEP Reports. 2019;1(3):203-21.
  • Culp KS, Fleming CR, Duffy J, Baldus WP, Dickson ER. Autoimmune associations in primary biliary cirrhosis. Mayo Clin Proc. 1982;57(6):365-370.
  • Palabıyıkoğlu M. Primer Biliyer Siroz. Turkiye Klinikleri Journal of Microbiology Infection. 2003;2(3):166-172.
  • Ghent CN, Bloomer JR, Klatskin G. Elevations in skin tissue levels of bile acids in human cholestasis: relationto serum levels and to pruritus. Gastroenterology. 1977;73(5):1125–1130.
  • Tekin F, Görümlü G, Yüce G, Soydan S, Özütemiz Ö, İlter T. Multipl myelom ve primer biliyer siroz birlikteliği: Olgu sunumu. Akademik Gastroenteroloji Dergisi. 2008;7(2):111-113.
  • Christensen E, Crowe J, Doniach D, Popper H, Ranek L, Rodes J, et al. Clinical pattern and course of disease in primary biliary cirrhosis based on analysis of 236 patients. Gastroenterology. 1980; 78(2):236-46.
  • Nijhawan PK, Therneau TM, Dickson ER, Boynton J, Lindor K D. Incidence of cancer in primary biliary cirrhosis: the Mayo experience. Hepatology. 1999; 29(5):1396-1398.
  • Goudie BM, Burt AD, Boyle P, Macfarlane G, Birnie GG, Mills PR, et al. Breast cancer in women with primary biliary cirrhosis. BMJ 1985; 291(6509):1597-1598.

Yeni Tanı Primer Biliyer Kolanjitli Hasta: Olgu Sunumu

Year 2020, Volume: 17 Issue: 3, 492 - 494, 25.12.2020
https://doi.org/10.35440/hutfd.733455

Abstract


Primer biliyer kolanjit (PBK) etiyolojisi bilinmeyen, çoğunlukla orta yaş kadınların etkilendiği, küçük safra kanallarında hasarın eşlik ettiği, yavaş ilerleyen, kronik kolestatik granülomatöz bir karaciğer hastalığıdır. PBK, portal hipertansiyon veya karaciğer yetmezliği gibi ciddi hastalıklara neden olup sonrasında siroza ilerleyebilir. Bu vakada olduğu gibi non-spesifik semptomlarla gelebileceği unutulmamalı, ayrıntılı anamnez ve şüphelenilen hastalarda gerekli laboratuvar tetkikleri ile tanı kesinleştirilmelidir.

References

  • Santiago P, Scheinberg AR, Levy C. Cholestatic liver diseases: new targets, new therapies. Therapeutic Advances in Gastroenterology. 2018;11(1):1-15.
  • .Gershwin ME, Mackay IR. The causes of primary biliary cirrhosis: convenient and in convenient truths. Hepatology. 2008;47(2):737-745.
  • Tkcv.org [homepage on the Internet]. Primer biliyer kolanjit (Primer-biliyer siroz) Türkiye-Azerbaycan Ortak Hepatoloji Kursu [updated 29 Eylül 2017; cited mart 2020] Available from: www.tkcv.org
  • Malik A, Kardashian AA, Zakharia K, Bowlus CL, Tabibian JH. Pre-ventative care in cholestatic liver disease: Pearls for the specialist and subspecialist. LiverResearch. 2019;3(2):118-127.
  • Corpechot C, Poupon R, Chazouilleres O. New treatments / targets for primary biliary cholangitis. JHEP Reports. 2019;1(3):203-21.
  • Culp KS, Fleming CR, Duffy J, Baldus WP, Dickson ER. Autoimmune associations in primary biliary cirrhosis. Mayo Clin Proc. 1982;57(6):365-370.
  • Palabıyıkoğlu M. Primer Biliyer Siroz. Turkiye Klinikleri Journal of Microbiology Infection. 2003;2(3):166-172.
  • Ghent CN, Bloomer JR, Klatskin G. Elevations in skin tissue levels of bile acids in human cholestasis: relationto serum levels and to pruritus. Gastroenterology. 1977;73(5):1125–1130.
  • Tekin F, Görümlü G, Yüce G, Soydan S, Özütemiz Ö, İlter T. Multipl myelom ve primer biliyer siroz birlikteliği: Olgu sunumu. Akademik Gastroenteroloji Dergisi. 2008;7(2):111-113.
  • Christensen E, Crowe J, Doniach D, Popper H, Ranek L, Rodes J, et al. Clinical pattern and course of disease in primary biliary cirrhosis based on analysis of 236 patients. Gastroenterology. 1980; 78(2):236-46.
  • Nijhawan PK, Therneau TM, Dickson ER, Boynton J, Lindor K D. Incidence of cancer in primary biliary cirrhosis: the Mayo experience. Hepatology. 1999; 29(5):1396-1398.
  • Goudie BM, Burt AD, Boyle P, Macfarlane G, Birnie GG, Mills PR, et al. Breast cancer in women with primary biliary cirrhosis. BMJ 1985; 291(6509):1597-1598.
There are 12 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Case Report
Authors

Nuray Kıvanç Terzi 0000-0002-2595-2716

Mehmet Sidar Güler 0000-0001-6376-7020

Dursun Çadırcı 0000-0003-0969-382X

Ahmet Uyanıkoğlu 0000-0003-4881-5244

Publication Date December 25, 2020
Submission Date May 7, 2020
Acceptance Date December 18, 2020
Published in Issue Year 2020 Volume: 17 Issue: 3

Cite

Vancouver Kıvanç Terzi N, Güler MS, Çadırcı D, Uyanıkoğlu A. Yeni Tanı Primer Biliyer Kolanjitli Hasta: Olgu Sunumu. Harran Üniversitesi Tıp Fakültesi Dergisi. 2020;17(3):492-4.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty